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In Depth 30 Oct 2024

Could next-generation “switchable” CAR-T cells help improve the safety and efficacy of CAR-T therapies?

…exploration for the creation of these so-called next-gen CAR-T therapies is “switchable” CAR-T cells, which essentially offer more control over the activation of CAR-T treatments. In this article, we take…

October 30, 2024 - 8 minutesmins - By Willow Shah-Neville

In Depth 11 Oct 2021

A Cure for Cancer? How CAR-T Cell Therapy is Revolutionizing Oncology

…of leukemia in compassionate cases. Bellicum Pharmaceuticals in the US is developing a similar technology called GoCAR-T that requires the drug rimiducid to activate the CAR T-cells. Unlike other CAR-T…

October 11, 2021 - 10 minutesmins - By Clara Rodríguez Fernández

In Depth 9 Dec 2024

CAR-T cell therapy for lupus: An emerging field with great potential

…Therapeutics’ CAR-T cell therapy for lupus enters phase 2 trial Cartesian Therapeutics is very much pushing ahead with its CAR-T candidate for lupus, as the company announced in July 2024…

December 9, 2024 - 10 minutesmins - By Willow Shah-Neville

Best in Biotech 21 Mar 2024

Eight CAR-T cell therapy companies you should know about

…CAR-T cell therapy candidates in the clinic. Table of contents Allogene Therapeutics Allogene Therapeutics aims to tackle the limitations of autologous CAR-T therapies by developing allogeneic CAR-T cell therapy products….

March 21, 2024 - 9 minutesmins - By Roohi Mariam Peter

In Depth 4 Oct 2023

CAR-NK: Can natural killer cell therapy pick up from where CAR-T left off?

…experienced with CAR-T therapy is cytokine release syndrome (CRS). This occurs when the immune system goes on overdrive because of the presence of the CAR-T cells. This triggers a storm…

October 4, 2023 - 7 minutesmins - By Roohi Mariam Peter

Streamlining CAR-T cell therapy manufacturing: a platform approach

…organization to deliver the CAR gene to a patient’s T cells and expand them into the final CAR-T therapy product, increasing manufacturing efficiency. Test-taking cells Once the CAR-T therapy has…

February 7, 2023 - 7 minutesmins - By Alexander Burik

In Depth 13 Dec 2023

Revolutionizing glioblastoma treatment: how CAR-T cell therapy could be used as a cure

…beginning to focus on two-pronged approaches, either using CAR-T therapy along with another type of treatment, or CAR-T therapies that target more than one antigen. Some of these approaches have…

December 13, 2023 - 8 minutesmins - By Willow Shah-Neville

News and Trends 20 Dec 2017

How to Deal with Regulations to Get Approval for CAR-T Cells

…this high: together, the IPOs of six CAR-T biotechs reached €800M in 2015. Initial public offerings of CAR-T companies between 2011 and 2016 It is commonly accepted that pharmaceutical drugs…

December 20, 2017 - 8 minutesmins - By Timothé Cynober

Interview 13 Jun 2018

CAR-T Brings Hope for Cancer Patients, But Challenges Lie Ahead

…killing solid tumors than conventional CAR-T approaches. It’s being explored by biotech companies such as TC Biopharm, GammaDelta Therapeutics or Gadeta. Using CAR-T cells from donors Both CAR-T cell therapies…

June 13, 2018 - 5 minutesmins - By Alexander Burik

Interview 19 Feb 2018

Taking CAR-T Cells Beyond Cancer: A New Therapy for Autoimmune Disease

…CAR-T cell therapy. CAR-T cells are changing the way cancer is treated, achieving huge remission rates in patients with severe forms of cancer. The gene editing technology saw its two…

February 19, 2018 - 9 minutesmins - By Clara Rodríguez Fernández

CA illustration explanatory labiotech T cell solid tumor cover art 1

Cell avidity-tuning ensures safe CAR-T therapy for solid tumors

…remains a major impediment to the advancement of CAR-T therapies. Unlike hematological malignancies where CAR-T therapy has achieved remarkable results due to the presence of tumor-specific targets, solid tumors generally…

May 14, 2024 - 5 minutesmins - By External Contributor

News and Trends 12 Jan 2016

Cellectis has Discovered an ‘On-Switch’ to Make CAR-T Safer and Better Controlled

…in how the CAR-T cells are deployed, taken up and act on cancerous cells. Simply put, there’s a lot of fine-tweaking and R&D to be done before CAR-T can truly…

January 12, 2016 - 3 minutesmins - By Dani Bancroft

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Search Results for: CAR-T

Could next-generation “switchable” CAR-T cells help improve the safety and efficacy of CAR-T therapies?

A Cure for Cancer? How CAR-T Cell Therapy is Revolutionizing Oncology

CAR-T cell therapy for lupus: An emerging field with great potential

Eight CAR-T cell therapy companies you should know about

CAR-NK: Can natural killer cell therapy pick up from where CAR-T left off?

Streamlining CAR-T cell therapy manufacturing: a platform approach

Revolutionizing glioblastoma treatment: how CAR-T cell therapy could be used as a cure

How to Deal with Regulations to Get Approval for CAR-T Cells

CAR-T Brings Hope for Cancer Patients, But Challenges Lie Ahead

Taking CAR-T Cells Beyond Cancer: A New Therapy for Autoimmune Disease

Cell avidity-tuning ensures safe CAR-T therapy for solid tumors

Cellectis has Discovered an ‘On-Switch’ to Make CAR-T Safer and Better Controlled

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The top biotech deals of March 2025

The biggest biotech funding rounds in March 2025

Join the webinar: AI in antibody discovery - from in silico analysis to AI-enabled data management

Beyond amyloid: The search for the next big thing in Alzheimer’s treatment

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

The top biotech deals of March 2025

The biggest biotech funding rounds in March 2025

Join the webinar: AI in antibody discovery - from in silico analysis to AI-enabled data management

Beyond amyloid: The search for the next big thing in Alzheimer’s treatment

Connect with decision-makers and researchers worldwide for collaborative opportunities

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