Danish ‘safer’ vaccine for Smallpox gets US order worth €90M

24/05/2016 - 2 minutes

Bavarian Nordic will receive €90M from the US’ BARDA for its nonreplicating smallpox vaccine – which can be administered to people with conditions like HIV.

bavarian_nordic_imvamune_smallpox_nonreplicatingBavarian Nordic is one of the Copenhagen-based Biotechs you need to know which is developing cancer immunotherapies and vaccines against infectious diseases.

Its infectious disease programme is based on their vaccine technology which uses an  attenuated version of the Modified Vaccinia Ankara (MVA) virus. This virus is unable to replicate, so it has a better safety profile.

Bavarian Nordic’s strategy was already successful in IMVAMUNE, a novel smallpox vaccine. Traditional smallpox vaccines are based on replicating virus strains, and can’t be administered to certain people – including those with HIV or atopic dermatitis (a severe skin condition).

Now, the Biomedical Advanced Research and Development Authority (BARDA), a division of the US government, has ordered a bulk supply of this vaccine – worth around €90M ($100M).

The US government already had an emergency stockpile of IMVAMUNE,

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