Galapagos is starting a new PhaseIIb/III clinical trial for ulcerative colitis that has triggered a €9.4M milestone payment from Gilead. Can this partnership beat out its many competitors?
Galapagos is one of the few billion-euro biotechs in Europe, boasting top-level partnerships with AbbVie for cystic fibrosis and MorphoSys for inflammatory diseases. The company now has news from its collaboration with Gilead: filgotinib has started a Phase IIb/III trial in ulcerative colitis. With this successful step in clinical development, Galapagos will receive a €9.4M milestone payment.
Filgotinib is already in Phase III for rheumatoid arthritis and Crohn’s disease. Although rheumatoid arthritis is a big market expected to hit an overwhelming €76B ($80.7B) by 2020, it is already crowded with big players. Humira (adalimumab), the top-selling drug developed by AbbVie, generated €13B ($14B) last year, and will soon be replaced by biosimilars in the pipelines of Boehringer Ingelheim, MSD, Amgen, Pfizer and Novartis’