€31M goes to a 15-month old Start-up tackling the leading cause of Dwarfism

05/10/2015 - 2 minutes

TherAchon is a 15-month old start-up from the Nice area (France) which has attracted some serious US investors as of late, drawn by their pioneering protein therapy for Achondroplasia (the leading cause of Dwarfism). OrbiMed have now joined New Enterprise Associates and Versant Ventures in a €31 million series A pot for their pre-clinical candidate.

Picture1Achondroplasia is caused by a point mutation in the fibroblast growth factor receptor 3 (FGFR3) gene causing stunted bone growth during development and cartilage malformations. Occurring in 1 for every 25,000 live births, it is therefore the most common cause of Dwarfism.

Founded by Elivre Gouze, a senior researcher at Inserm and the University of Nice Sophia Antipolis, in 2014 therAchon was born following a paper published in Science Translational Medicine in 2013. The paper’s research team (led by Gouze) showed that soluble replacement of the FGFR3 protein actually increased bone length in mice,

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