Squeezing Cells: A Revolutionary Cancer Drug Delivery Platform for €455M?

09/12/2015 - 3 minutes

The MIT spin-off SQZ Biotech has an invention (Cell SQueeZe) which could make vector drug delivery in Cancer a thing of the past… Roche thinks so too, and has now acquired this small biotech for €455M upfront.

sqz_roche_cell_therapy_acquisitionMIT Professors Klavs Jensen, Robert Langer and PhD Student Armon Sharei were focused on developing a more effective system for delivering materials directly into the cell cytosol (internal cell matter) – a significant challenge in many research and therapeutic applications.

Their team’s work, supported by the US NIH and Koch Institute for Integrative Cancer Research, led to the development of the CellSqueeze platform. Thus, SQZ Biotech was founded, through which the team aims to continue to explore and develop the potential of this promising technology.

cellsqueeze_SQZ_roche_drug_delivery_chemo_cell

The CellSqueeze Platform is a novel method of drug delivery (as well as other small molecules) into cells which doesn’t require a vector (e.g. liposomes, viruses).

It was proven to be far superior to traditional cell penetrating technology techniques such as electroportion or transmembrane proteins (by 10-100 times) and also is significantly less toxic to non-target cells,

This content is available exclusively to our paying members.

Our members receive the following benefits:

  • Unlock premium articles
  • Download our industry reports
  • Remove all banner ads
  • Access 1,500+ archived posts
  • Support our independent media
Already a member? Sign in
ADVERTISEMENT
Do you want to remove this advert? Become a member!
ADVERTISEMENT
Do you want to remove this advert? Become a member!

Support Us

Become a Member