In Depth 21 Feb 2024 Cytokine release syndrome: how pharma is tackling a 21st century disease Explore the frontier of biotech’s battle against cytokine release syndrome (CRS), from historical setbacks to cutting-edge solutions. February 21, 2024 - 6 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Opinion 18 Dec 2023 What to expect from biotech clinical trials in the coming year As cancer research has seen an increase in funding lately, here are some of the key clinical trends that you can expect in 2024. December 18, 2023 - 11 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Opinion 29 Nov 2023 Redefining drug development: the trailblazing evolution of the pharmaceutical industry Drug discovery and development is a long, costly, and high-risk process that takes over 10 to 15 years with an average cost of over $1 to $2 billion for each new drug to be approved for clinical use. For any pharmaceutical company or academic institution, it is a big achievement to advance a drug candidate […] November 29, 2023 - 9 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Opinion 1 Nov 2023 Could this be the start of a new era for PI3K drugs? There is hope that a rich biotech pipeline will produce a second generation of PI3K drugs, a type of kinase inhibitor, after issues with the first generation from the class had brought up concerns. Phosphoinositide 3-kinases (PI3K) drugs work by inhibiting a pathway that plays a role in cell metabolism, growth, proliferation and survival that […] November 1, 2023 - 7 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Opinion 25 Oct 2023 Microbiome: are we ready for third generation live biotherapeutics? The microbiome sector has come a long way. From liquidizing fecal matter in a kitchen appliance for direct insertion into the intestine to the encapsulation of dried matter for oral delivery; and now to the creation of live biotherapeutics, single drug products of multiple bacterial strains. The application of microbiome therapeutics is also broadening – […] October 25, 2023 - 11 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Expert Advice 23 Oct 2023 Top 10 tips from an expert on how to start an early phase clinical trial Early phase clinical trials can be complicated and time-consuming, with their success dependent on several different factors. The outcome of these early phase clinical trials will determine the future of your drug development project, and so ensuring safety and efficiency at every step since the start is vital for its overall success. The clinical operations […] October 23, 2023 - 8 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Opinion 27 Sep 2023 Tackling the skilled labor shortage in biopharma manufacturing By Brandy Bullen, founder & CEO of Sequoia Consulting Group The biopharma manufacturing sector stands at a critical juncture as it grapples with an increasingly pronounced skilled labor shortage. In an era marked by rapid advancements in biotechnology and the growing demand for innovative therapies, the industry finds itself facing a pressing challenge – the […] September 27, 2023 - 6 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Opinion 20 Sep 2023 The next frontier in genomic technologies for rare diseases By Neil Ward, VP and General Manager at PacBio EMEA It’s been 40 years since the passage of the Orphan Drug Act, which catalyzed the development of hundreds of therapies for rare diseases, with more than half approved in the last decade. More recently in 2022, the U.K. government launched a Rare Diseases Action Plan […] September 20, 2023 - 7 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Expert Advice 28 Jul 2023 What you need to know about the EU HTA regulation before deadline By Anke van Engen, senior principal, EMEA value & payer evidence, IQVIA, and Dima Samaha, senior principal, EMEA value & payer evidence, IQVIA The European Union (EU) comprises 27 member states (MS) with varying laws, processes and regulatory standards. This variation has led to a complex data landscape for health technologies and drug therapeutics developers, […] July 28, 2023 - 7 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
Opinion 11 Jul 2023 Unlocking the power of mRNA technology By Yochi Slonim, CEO and co-founder of Anima Biotech mRNA technology has gained widespread recognition due to its role in the development of vaccines, such as those used against COVID-19; however, the scope of mRNA extends far beyond vaccines, offering a range of applications for addressing different conditions. Vaccines represent a notable application of mRNA […] July 11, 2023 - 4 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
News and Trends 11 Jul 2023 Inhaled mRNA medicines redefine respiratory disease treatment By Carsten Rudolph, co-founder and CEO of Ethris Advancements in mRNA technology have led to the development of inhaled mRNA medicines, which hold tremendous potential for revolutionizing the treatment of respiratory diseases, an area with high unmet needs. However, the primary hurdle in its clinical application lies in the identification of a delivery system that […] July 11, 2023 - 3 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email
In Depth 10 Jul 2023 “Ready-to-use” enzymatically produced cell-free synthetic DNA in mRNA manufacturing By Ashish Dhir, PhD and Amy Walker, PhD, 4basebio The pace, efficacy and scalability with which the success of mRNA vaccines against COVID-19 was demonstrated opened endless possibilities for mRNA medicine in broad areas of infectious diseases, cancers, protein-encoding replacement therapies. The advantages of RNA medicine are obvious, with the ease and speed of design […] July 10, 2023 - 6 minutesmins - By External Contributor Share WhatsApp Twitter Linkedin Email