Learn about the the use of kinases as therapeutics
Dysregulation or mutations in kinases can result in numerous diseases. In fact, over 85% of the human kinome is involved in at least one disease or disorder, including cancer, cardiovascular disease, and neurological disorders.
Of over 500 kinases, only 80 have been targeted for the treatment of diseases so far.
For drug developers, resistance and toxicity remain major challenges.
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In this report, we study the science behind the human kinome, analyze the use of kinases as therapeutics, and discuss the exciting future of kinase inhibitors.