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Best in Biotech 30 Jan 2025

Seven genome sequencing companies to look out for

…DNA template to create long single-stranded DNA molecules to avoid errors such as index hopping – when sequencing reads are incorrectly assigned to the wrong sample in a pool. Its…

January 30, 2025 - 9 minutesmins - By Roohi Mariam Peter

cancer dna damage repair duke street bio parp

News and Trends 25 May 2022

Duke Street Bio enters stage with next-generation cancer therapies

…chairman and co-founder of Duke Street Bio, told us. Other companies researching cancer therapies based on DNA repair include Artios, which is developing DNA damage response inhibitors and raised €129M…

May 25, 2022 - 3 minutesmins - By Susannah Rodgers

News and Trends 17 Oct 2022

PerkinElmer’s Horizon Discovery: the lowdown on base editing

…the human genome. However, the creation of double stranded DNA breaks (dsDNA), while central to the function of the “bacterial immune system” from which CRISPR was derived, is not ideal…

October 17, 2022 - 5 minutesmins - By Jim Cornall

News and Trends 1 Aug 2022

BioMed X Institute and Merck start new oncology research project

…main objective of this research group is to develop an atlas of extrachromosomal DNA (ecDNA) in human cancer tissues and trace back the mechanisms of ecDNA formation and function. Extrachromosomal…

August 1, 2022 - 3 minutesmins - By Jim Cornall

ovarian cancer astrazeneca merck lynparza dna repair

News and Trends 19 Jun 2019

EU Gives Lynparza Green Light as First-Line Ovarian Cancer Treatment

…disrupting DNA damage repair in cancer. Martin’s company Artios Pharma is developing drugs targeting a different DNA damage repair protein. The French biotech Onxeo is developing DNA drugs preventing the…

June 19, 2019 - 3 minutesmins - By Jonathan Smith

Best in Biotech 6 Oct 2022

15 biotech companies shaking up the scene in Cambridge

…2016 Artios Pharma is developing drugs that inhibit an enzyme called DNA polymerase theta, which plays a role in multiple DNA repair processes. The levels of this enzyme are typically…

October 6, 2022 - 9 minutesmins - By Helen Albert

In Depth 6 Feb 2018

CRISPR/Cas9: Could the Gene Editing Technology be the Future of Drug Discovery?

…a double-strand break in the DNA, which is repaired by the cell’s error-prone DNA repair machinery. That alone is usually knocks-out the gene of interest and allows scientists to study…

February 6, 2018 - 9 minutesmins - By Melanie De Almeida

Startup Scout 26 Aug 2022

Epic Bio makes gene therapies by editing the epigenome

…control which genes become proteins. Epic Bio’s therapies involve fusing together a protein that binds to DNA with a so-called modulator protein that can make epigenetic changes to the DNA…

August 26, 2022 - 4 minutesmins - By Jonathan Smith

News and Trends 28 Nov 2022

Localizing BRCA gene mutations to better treat ovarian cancer

…the DNA-binding domain, the drug is actually much more effective.” DNA-binding domains are protein motifs that are capable of binding to the DNA, and are involved in the regulation of…

November 28, 2022 - 5 minutesmins - By Jim Cornall

Podcast 5 Apr 2024

Colossal Biosciences’ 2028 goal: Bringing back the woolly mammoth

…at the ancient DNA assembly that was needed. They also looked to improve the pipelines for ancient DNA, which is a different process to non-ancient and massively degraded DNA. Harnessing…

April 5, 2024 - 8 minutesmins - By Jim Cornall

News and Trends 25 Feb 2021

Legal Fights Accompany Big Fundraises in Liquid Biopsy Scene

…identify solid tumors from tiny amounts of cancer DNA in a blood sample, which is known as circulating tumor (ct)DNA. This technology could provide an easier diagnostic alternative to invasive…

February 25, 2021 - 5 minutesmins - By Anita Chakraverty

Best in Biotech 4 Jul 2025

14 biotech companies to know in the Boston area in 2025

…DNA repair and cancer survival but have historically been very difficult to target with drugs. Their lead candidate, MOMA‑313, is a highly selective oral inhibitor of DNA polymerase theta, an…

July 4, 2025 - 15 minutesmins - By Jules Adam

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Search Results for: dna

Seven genome sequencing companies to look out for

Duke Street Bio enters stage with next-generation cancer therapies

PerkinElmer’s Horizon Discovery: the lowdown on base editing

BioMed X Institute and Merck start new oncology research project

EU Gives Lynparza Green Light as First-Line Ovarian Cancer Treatment

15 biotech companies shaking up the scene in Cambridge

CRISPR/Cas9: Could the Gene Editing Technology be the Future of Drug Discovery?

Epic Bio makes gene therapies by editing the epigenome

Localizing BRCA gene mutations to better treat ovarian cancer

Colossal Biosciences’ 2028 goal: Bringing back the woolly mammoth

Legal Fights Accompany Big Fundraises in Liquid Biopsy Scene

14 biotech companies to know in the Boston area in 2025

Subscribe to our newsletter to get the latest biotech news!

10 oncology deals in 2025 spotlight where industry leaders are betting big

10 biotech companies leading the way in Denmark

Webinar: Advancements in antimalarial drug discovery and development

Six psychedelic drug companies aiming to revolutionize mental health treatment

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

10 oncology deals in 2025 spotlight where industry leaders are betting big

10 biotech companies leading the way in Denmark

Webinar: Advancements in antimalarial drug discovery and development

Six psychedelic drug companies aiming to revolutionize mental health treatment

Connect with decision-makers and researchers worldwide for collaborative opportunities

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Advertise with us

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