Immunotherapy Archives

Podcast 8 Sep 2023

Beyond Biotech podcast 62 – cytokine-based drugs

As September 8 is Stand Up To Cancer Day, one area of promising research lies in cytokine-based drugs, which have the potential to activate T cells against tumors. Historically, toxicity from systemic cytokine treatment has remained a challenge, prompting several companies to explore ways to “engineer” drugs with modified cytokine molecules like interleukin 2 (IL-2) […]

September 8, 2023 - 2 minutesmins - By Jim Cornall

Best in Biotech 5 Sep 2023

Five recent advancements in ovarian cancer research over the past year

With around 7500 new cases reported in the U.K. alone every year, ovarian cancer may occur because of the inheritance of faulty genes like BRCA. Although the exact reason for cancer-causing genetic mutations is unknown – as with all other kinds of cancer – ovarian cancer research has shown that the risk increases with age, […]

September 5, 2023 - 9 minutesmins - By Roohi Mariam Peter

In Depth 24 Jul 2023

Sarcoma research: is a breakthrough in sight?

Among the rarest forms of cancers, sarcomas develop in the bones and connective tissues that support structures in the body like blood vessels, nerves and joints. This year, around 13,400 new cases of soft tissue sarcomas are estimated to be diagnosed in the U.S. alone, according to the American Cancer Society. As July marks Sarcoma […]

July 24, 2023 - 7 minutesmins - By Roohi Mariam Peter

News and Trends 20 Jul 2023

CatalYm shows importance of GDF-15 in tumor immunotherapy resistance

CatalYm has published preclinical data in Nature Communications that reveal the central role of Growth Differentiation Factor-15 (GDF-15) in the resistance of tumors to current immunotherapy. CatalYm said the findings further highlight the therapeutic significance of its proprietary anti-GDF-15 antibody candidate, visugromab, currently in advanced phase 2 clinical studies. The foundational research, which was performed […]

July 20, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 4 Jul 2023

Exeliom Biosciences closes €24M financing for lead candidate

Exeliom Biosciences has completed a €24 million ($26 million) Series A to progress the clinical development of its therapeutic pipeline. This includes several clinical trials of EXL01, a novel immunotherapy with applications in cancer and in infectious diseases. This follows on from the initial closing of €7 million ($7.6 million) in 2018, a first extension […]

July 4, 2023 - 3 minutesmins - By Jim Cornall

In Depth 27 Jun 2023

The promise of immunotherapy for autoimmune diseases

Our immune system serves as the body’s chief line of defense against harmful invaders. But what happens when this mighty defense mechanism turns on its own host, launching an assault on healthy cells and tissues? For the millions of people battling autoimmune diseases, this can severely affect their lives. However, advances in immunotherapy have revolutionized […]

June 27, 2023 - 9 minutesmins - By Roohi Mariam Peter

In Depth 9 Jun 2023

Enhancing canine wellness: The promise of immunotherapy for dogs

Given that dogs are widely regarded as ‘man’s best friend’, it makes sense that we are constantly striving to find ways to improve canine health and extend their lives. One method that has been – and is still being – explored is the use of immunotherapy, which uses a dog’s own immune system to fight […]

June 9, 2023 - 8 minutesmins - By Willow Shah-Neville

Best in Biotech 6 Jun 2023

Ten Swedish companies spearheading the country’s biotech scene

Known for its abundant forests, smorgasbords and not to mention the famed Europop group ABBA, Sweden has a thriving economy that largely depends on manufacturing and exports. And the country’s life science sector having recorded a net turnover of almost SEK 365 billion ($33.5 million) in 2020, is ever-growing. Home to more than 1,000 life […]

June 6, 2023 - 10 minutesmins - By David Cox

In Depth 11 May 2023

Battling food allergies: emerging immunotherapies

While for most individuals, picking a restaurant to dine at could simply be based on what they might be craving at the moment, for about one to five per cent of the world’s population, this is a well-thought-out decision that involves ensuring there wouldn’t be any cross-contamination in the food which is bound to trigger […]

May 11, 2023 - 9 minutesmins - By Roohi Mariam Peter

Best in Biotech 9 May 2023

5 cancers that immunotherapy can cure

Cancer immunotherapy dates back to 1891, when William Coley became the first person to try and harness the immune system to treat cancer. Since then, immunotherapy has become the mainstay of cancer treatment and is being used in the fight against many different types of cancer. When the first immune checkpoint inhibitor – which works […]

May 9, 2023 - 7 minutesmins - By Willow Shah-Neville

In Depth 3 May 2023

Immunotherapy in the fight against solid tumors

Ever since William Coley first attempted to harness the immune system in 1891 to treat bone cancer, immunotherapy has been explored in the treatment of various different cancers – both solid and liquid – and has revolutionized and rejuvenated the field of oncology. However, despite certain immunotherapy treatments having shown very promising results, such as […]

May 3, 2023 - 9 minutesmins - By Willow Shah-Neville

News and Trends 24 Apr 2023

RNA-based nanodrugs cause cancer cells to collapse – 80% survival rate for ovarian cancer in lab models

Researchers from Tel Aviv University in Israel have revealed details of a new approach to the treatment of ovarian cancer using RNA-based nanodrugs – demonstrating an 80% survival rate in lab models.In a study at Tel Aviv University, the protein CKAP5 (cytoskeleton-associated protein) was used for the first time as a therapeutic target for RNA-based […]

April 24, 2023 - 4 minutesmins - By Jim Cornall

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