Alzheimer's Archives

In Depth 13 Jun 2023

Abeta-targeting antibodies pave the way for Alzheimer’s disease vaccines

By Dr. Andrea Pfeifer, CEO of AC Immune SA The clinical success we’ve recently seen with two monoclonal antibodies that target the protein amyloid beta (Abeta) has provided hope for patients, a significant boost to the sector but also a strong validation of the “amyloid hypothesis”: removing Abeta plaques is a valid therapeutic strategy for […]

June 13, 2023 - 7 minutesmins - By External Contributor

AI artificial intelligence dementia alzheimer's

News and Trends 13 Jun 2023

How AI can advance research and treatment of CNS disorders

By Xiao Xu, senior research fellow, Cerevance The combination of large-scale biological datasets and developments in artificial intelligence (AI) has revolutionized our understanding and treatment of central nervous system (CNS) disorders. By leveraging AI’s computational power, researchers have been able to interrogate diverse datasets to provide insights into disease mechanisms, discover novel therapeutic compounds, detect […]

June 13, 2023 - 3 minutesmins - By External Contributor

Best in Biotech 12 Jun 2023

Six advancements in Alzheimer’s research over the past year

The most common cause of dementia, Alzheimer’s disease, is a brain disorder that is characterized by cognitive decline which often manifests itself through memory loss, feelings of disorientation and difficulty making decisions. Alzheimer’s occurs when there is an excessive accumulation of proteins in the brain, a hallmark feature of the disease. These proteins, namely, amyloid […]

June 12, 2023 - 12 minutesmins - By Roohi Mariam Peter

News and Trends 30 May 2023

New study reveals Alzheimer’s inflammation protection

A possible explanation has been found in a study for why apoE4, the most significant genetic risk factor associated with Alzheimer’s disease, fails to protect the brain from inflammation.Alzheimer’s disease is characterized by the accumulation of plaques of the amyloid-β protein, chronic inflammation and impaired neuronal function in the brain. The most significant genetic risk […]

May 30, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 25 May 2023

Researchers discover genetic variation offers Alzheimer’s disease clues

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease (AD), alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself. These new data support the idea that even […]

May 25, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 22 May 2023

Cancer implications as new molecule can kill ‘zombie’ cells

Over time, the body’s cells stop working properly and begin to accumulate, which eventually leads to tissues aging. Researchers at the UOC (Universitat Oberta de Catalunya) in Spain, in collaboration with the University of Leicester in the U.K. have discovered a new molecule that is able to destroy these old cells without affecting healthy ones. […]

May 22, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 16 May 2023

Researchers’ mutation discovery offers new Alzheimer’s hope

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting tens of millions of people worldwide, and it is the most common cause of dementia. Early-onset AD is typically associated with mutations in the genes APP, PSEN1, and PSEN2, leading to a more aggressive form of the disease with atypical symptoms. In contrast, the newly discovered […]

May 16, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 15 May 2023

Alzheimer’s drugs could result from immune brain cell discovery

A recent study published in Nature Neuroscience indicates that, contrary to common belief, the immune cells of the brain, known as microglia, are not all the same. Researchers found that a unique microglial subset with unique features and function is important for establishing proper cognitive functions in mice. Evidence for such microglial subsets exists also […]

May 15, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 9 May 2023

Ultra-long protein fibrils could help with early Alzheimer’s diagnosis

The early diagnosis and treatment of dementia such as Alzheimer’s disease is still a big challenge. It is already known that certain proteins in the cerebrospinal fluid can be used to diagnose Alzheimer’s disease. However, the current detection methods for such biomarkers by means of biochemical tests can only confirm and quantify the presence of […]

May 9, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 3 May 2023

Positive study results: Lilly’s Alzheimer’s drug slows patients’ decline

Eli Lilly and Company has announced positive results of the TRAILBLAZER-ALZ 2 phase 3 study showing that donanemab significantly slowed cognitive and functional decline in people with early symptomatic Alzheimer’s disease. Donanemab met the primary endpoint of change from baseline until 18 months on the integrated Alzheimer’s Disease Rating Scale (iADRS). The primary endpoint of […]

May 3, 2023 - 8 minutesmins - By Jim Cornall

Vaccines for difficult-to-treat diseases

Best in Biotech 12 Apr 2023

6 new vaccines being developed for difficult-to-treat diseases

There are several promising new vaccine candidates being developed for complex diseases that historically have been extremely difficult to find treatments and cures for. The development of these new vaccines could eventually lead to breakthrough treatments for diseases such as Alzheimer’s disease, HIV, Parkinson’s disease, Lyme disease, and breast cancer. According to the World Health […]

April 12, 2023 - 10 minutesmins - By Willow Shah-Neville

News and Trends 4 Apr 2023

Alzamend pushing ahead with Alzheimer’s vaccine trial

Alzamend Neuro, Inc. has announced the initiation of a phase I/IIA clinical trial for its immunotherapy vaccine (ALZN002) to treat mild to moderate dementia of the Alzheimer’s type. The purpose of the trial is to assess the safety, tolerability, and efficacy of multiple ascending doses of Alzamend Neuro’s ALZN002 compared with that of placebo in […]

April 4, 2023 - 4 minutesmins - By Jim Cornall

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T cell engagers: A promising, fast-growing field for cancer and autoimmune disease treatments

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Alzheimer’s

Abeta-targeting antibodies pave the way for Alzheimer’s disease vaccines

How AI can advance research and treatment of CNS disorders

Six advancements in Alzheimer’s research over the past year

New study reveals Alzheimer’s inflammation protection

Researchers discover genetic variation offers Alzheimer’s disease clues

Cancer implications as new molecule can kill ‘zombie’ cells

Researchers’ mutation discovery offers new Alzheimer’s hope

Alzheimer’s drugs could result from immune brain cell discovery

Ultra-long protein fibrils could help with early Alzheimer’s diagnosis

Positive study results: Lilly’s Alzheimer’s drug slows patients’ decline

6 new vaccines being developed for difficult-to-treat diseases

Alzamend pushing ahead with Alzheimer’s vaccine trial

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T cell engagers: A promising, fast-growing field for cancer and autoimmune disease treatments

The biggest biotech funding rounds in February 2025

Grab your free report on 3D organoids and explore their future potential

World Cancer Day: trends in cancer therapeutics to look forward to in 2025

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

T cell engagers: A promising, fast-growing field for cancer and autoimmune disease treatments

The biggest biotech funding rounds in February 2025

Grab your free report on 3D organoids and explore their future potential

World Cancer Day: trends in cancer therapeutics to look forward to in 2025

Connect with decision-makers and researchers worldwide for collaborative opportunities

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Advertise with us

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