Alzheimer's Archives

News and Trends 25 May 2023

Researchers discover genetic variation offers Alzheimer’s disease clues

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease (AD), alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself. These new data support the idea that even […]

May 25, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 22 May 2023

Cancer implications as new molecule can kill ‘zombie’ cells

Over time, the body’s cells stop working properly and begin to accumulate, which eventually leads to tissues aging. Researchers at the UOC (Universitat Oberta de Catalunya) in Spain, in collaboration with the University of Leicester in the U.K. have discovered a new molecule that is able to destroy these old cells without affecting healthy ones. […]

May 22, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 16 May 2023

Researchers’ mutation discovery offers new Alzheimer’s hope

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting tens of millions of people worldwide, and it is the most common cause of dementia. Early-onset AD is typically associated with mutations in the genes APP, PSEN1, and PSEN2, leading to a more aggressive form of the disease with atypical symptoms. In contrast, the newly discovered […]

May 16, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 15 May 2023

Alzheimer’s drugs could result from immune brain cell discovery

A recent study published in Nature Neuroscience indicates that, contrary to common belief, the immune cells of the brain, known as microglia, are not all the same. Researchers found that a unique microglial subset with unique features and function is important for establishing proper cognitive functions in mice. Evidence for such microglial subsets exists also […]

May 15, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 9 May 2023

Ultra-long protein fibrils could help with early Alzheimer’s diagnosis

The early diagnosis and treatment of dementia such as Alzheimer’s disease is still a big challenge. It is already known that certain proteins in the cerebrospinal fluid can be used to diagnose Alzheimer’s disease. However, the current detection methods for such biomarkers by means of biochemical tests can only confirm and quantify the presence of […]

May 9, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 3 May 2023

Positive study results: Lilly’s Alzheimer’s drug slows patients’ decline

Eli Lilly and Company has announced positive results of the TRAILBLAZER-ALZ 2 phase 3 study showing that donanemab significantly slowed cognitive and functional decline in people with early symptomatic Alzheimer’s disease. Donanemab met the primary endpoint of change from baseline until 18 months on the integrated Alzheimer’s Disease Rating Scale (iADRS). The primary endpoint of […]

May 3, 2023 - 8 minutesmins - By Jim Cornall

Vaccines for difficult-to-treat diseases

Best in Biotech 12 Apr 2023

6 new vaccines being developed for difficult-to-treat diseases

There are several promising new vaccine candidates being developed for complex diseases that historically have been extremely difficult to find treatments and cures for. The development of these new vaccines could eventually lead to breakthrough treatments for diseases such as Alzheimer’s disease, HIV, Parkinson’s disease, Lyme disease, and breast cancer. According to the World Health […]

April 12, 2023 - 10 minutesmins - By Willow Shah-Neville

News and Trends 4 Apr 2023

Alzamend pushing ahead with Alzheimer’s vaccine trial

Alzamend Neuro, Inc. has announced the initiation of a phase I/IIA clinical trial for its immunotherapy vaccine (ALZN002) to treat mild to moderate dementia of the Alzheimer’s type. The purpose of the trial is to assess the safety, tolerability, and efficacy of multiple ascending doses of Alzamend Neuro’s ALZN002 compared with that of placebo in […]

April 4, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 31 Mar 2023

€260M fund addresses dementia investment shortfall

EQT Life Sciences has closed its inaugural LSP Dementia Fund, raising approximately €260 million ($283 million) in fee-generating assets under management, meeting the hard cap and surpassing the target fund size of €100 million ($108.9 million). The LSP Dementia Fund is dedicated to investing in companies that are developing breakthrough drug therapies and medical technologies […]

March 31, 2023 - 3 minutesmins - By Jim Cornall

Best in Biotech 21 Mar 2023

5 advancements in Down syndrome research over the past year

It was in 1959 when an extra chromosome on the 21st pair in the human cell was discovered by French geneticist Jerome Jean Louis Marie Lejeune. This was followed by research in the discipline of cytogenetics – the study of chromosomes. This chromosomal aberration which affects around one in 1000 live births worldwide, is called […]

March 21, 2023 - 8 minutesmins - By Roohi Mariam Peter

News and Trends 8 Mar 2023

Could changing mRNA provide a new target for Alzheimer’s disease?

Reducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer’s disease in a mouse model. This is according to a new study in the open access journal PLOS Biology by Rui Zhang of Air Force Medical University in Xian, Shaanxi, China. The results highlight […]

March 8, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 8 Mar 2023

The challenges of tackling dementia in women

Dr Andrea Pfeifer, chief executive officer of AC Immune SA, talks to Labiotech about dementia research, and how dementia affects women. She also addresses how vital research is when it comes to addressing women’s health. Dementia is a leading cause of death in women, but it doesn’t get the attention of other diseases, such as […]

March 8, 2023 - 5 minutesmins - By Jim Cornall

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