AstraZeneca Archives

News and Trends 26 Nov 2020

AstraZeneca’s Covid-19 Vaccine Proves Its Worth in Phase III

A much anticipated Covid-19 vaccine, developed by the University of Oxford and AstraZeneca, achieved 70% efficacy in phase III interim data. While less effective on paper, it could prove cheaper and easier to distribute than its most advanced competitors. Scientists and politicians heartily received the announcement of promising interim clinical trial results from the Covid-19 […]

November 26, 2020 - 4 minutesmins - By Kostas Vavitsas

News and Trends 26 Mar 2020

Silence Therapeutics to Work with AstraZeneca in RNAi Deal Worth up to €3.6B

AstraZeneca is recruiting RNAi specialist Silence Therapeutics to develop treatments for cardiovascular, renal, metabolic, and respiratory diseases. RNA interference, or RNAi, is a relatively new field of medicine in which therapeutic small interfering (si)RNA molecules — known as siRNA molecules — can selectively block genes and thus inhibit the production of disease-causing proteins. John Strafford, […]

March 26, 2020 - 3 minutesmins - By Laura Cowen

News and Trends 7 Jan 2020

AstraZeneca Recruits RNA Biotech to Develop Metabolic Disease Therapies

The UK biotech MiNA Therapeutics has launched a collaboration with AstraZeneca to develop small activating RNA drugs, which could treat metabolic diseases using targets unreachable by current medications. According to the agreement, the two partners will carry out preclinical research with the aim of generating candidate drugs based on small activating RNA, or saRNA — […]

January 7, 2020 - 2 minutesmins - By Jonathan Smith

Expert Advice 11 Dec 2019

What Makes a Successful Biotech?

How does it feel to have co-developed the most successful drug in the world? This is something Jane Osbourn, now Chair of the Board at UK cell therapy biotech Mogrify, knows only too well. Early in her career, Osbourn was working as a postdoc in Cambridge and was persuaded to join a small, and at […]

December 11, 2019 - 12 minutesmins - By Helen Albert

News and Trends 31 Oct 2019

European Project Launches to Tailor Autoimmune Disease Treatments

Public and private organizations across Europe will pool their resources in an €80M project to discover biomarkers that can predict which patients will respond best to treatments for autoimmune diseases. The project is called Taxonomy, Treatments, Targets and Remission, or 3TR for short, and is funded by the EU’s Innovative Medicines Initiative for the next […]

October 31, 2019 - 2 minutesmins - By Jonathan Smith

Interview 23 Oct 2019

Channeling the Power of AI into Personalizing Medicine

Artificial intelligence has been much discussed of late, but will it really help us solve important problems like how to bring personalized medicine to as many patients as possible? Kate Hilyard, COO of Healx in Cambridge in the UK, believes it can. Getting a drug to clinical trials currently requires a large investment of both […]

October 23, 2019 - 7 minutesmins - By Helen Albert

Expert Advice 8 Oct 2019

Why Good Teamwork is Key to Biotech Success

Teamwork is important throughout the development of a company, but never more so than in the early stages of a startup. Charlotte Edenius, co-founder and VP Business and Clinical development at Gesynta Pharma in Sweden, knows this well. With more than 20 years experience working in the industry, she knows how important it is for biotech leaders […]

October 8, 2019 - 10 minutesmins - By Helen Albert

cardiology astrazeneca novartis cardiovascular disease

News and Trends 5 Sep 2019

Top Cardiology Biotech News from the ESC Conference 2019

Many cardiology companies and academics gathered in Paris earlier this week to showcase their latest research into cardiovascular diseases. Read on for a roundup of the most exciting cardiology news from the biotech scene. The European Society of Cardiology teamed up with the World Heart Federation this year to arrange a conference themed on global […]

September 5, 2019 - 4 minutesmins - By Jonathan Smith

ovarian cancer astrazeneca merck lynparza dna repair

News and Trends 19 Jun 2019

EU Gives Lynparza Green Light as First-Line Ovarian Cancer Treatment

The DNA damage repair drug olaparib (Lynparza), developed by AstraZeneca and Merck, has been approved by the EU as a first-line treatment preventing the return of ovarian cancer after initial chemotherapy. The drug has already been approved by the EU and the FDA as a maintenance treatment for relapsed ovarian cancer, and as a therapy […]

June 19, 2019 - 3 minutesmins - By Jonathan Smith

In Depth 9 Apr 2018

Are PD-1 and PD-L1 Checkpoint Inhibitors As Good As We Thought?

Checkpoint inhibitors, especially those targeting PD-1 and PD-L1, are exploding in popularity. But how much of it is hype? The pipelines of biotech and pharma are filling up with combination therapies for anti-PD-1 and PD-L1 antibodies. According to the Cancer Research Institute, there are now over 1,500 clinical trials testing the popular checkpoint inhibitors, a dramatical increase […]

April 9, 2018 - 4 minutesmins - By Clara Rodríguez Fernández

News and Trends 5 Mar 2018

Danish Biotech Starts Phase III Atopic Dermatitis Trial With Failed Asthma Treatment

Danish biotech LEO Pharma started a Phase III trial in atopic dermatitis with an antibody that AstraZeneca dropped after failing two Phase III trials in asthma. LEO Pharma is taking over the development of the antibody tralokinumab from AstraZeneca to treat atopic dermatitis after the drug failed multiple Phase III studies for treating asthma. In […]

March 5, 2018 - 2 minutesmins - By Alexander Burik

News and Trends 28 Feb 2018

Yet Another Checkpoint Inhibitor Goes to Trial with Bavarian Nordic’s Cancer Vaccine

Bavarian Nordic and AstraZeneca collaborate on a treatment that uses a cancer vaccine along with a checkpoint inhibitor to treat colorectal and pancreatic cancer. Notably, this is the third checkpoint inhibitor to be tested with Bavarian Nordic’s vaccine. A Phase I/II trial will evaluate the safety and efficacy of using Bavarian Nordic’s cancer vaccine CV301 in […]

February 28, 2018 - 3 minutesmins - By Alexander Burik

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