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parkinsons disease treefrog therapeutics cell therapy

News and Trends 9 Jun 2020

French Manufacturing Plant Launches to Make Cell Therapy Cheap and Scalable

The Bordeaux-based company Treefrog Therapeutics has opened an industrial demonstration plant with the aim of producing cell therapies 10 times more efficiently than with current technology. The €2M plant occupies an area around a fifth of the size of a football field and is expected to produce 80 billion cells per year when it reaches […]

June 9, 2020 - 4 minutesmins - By Jonathan Smith

Engineered B cells

In Depth 25 May 2020

Could Cell Therapy Target the Symptoms of Severe Covid-19?

The excessive inflammatory response seen in the most serious cases of Covid-19, along with shortages of ventilators, has caused a healthcare crisis in many countries around the world. Could cell therapy provide an answer to this dilemma? Most people who become infected with Covid-19 experience symptoms such as a dry cough and mild fever, and […]

May 25, 2020 - 5 minutesmins - By Helen Albert

pluristem cell therapy covid 19 coronavirus

News and Trends 29 Apr 2020

Pluristem Scores €50M From EIB to Develop Covid-19 Cell Therapy

Israeli cell therapy biotech Pluristem Therapeutics has secured up to €50M in non-dilutive funding from the European Investment Bank to progress its coronavirus-targeting cell therapy to phase III. The partners plan to sign the funding agreement at the end of April and Pluristem will initially receive €20M followed by two further installments totaling up to […]

April 29, 2020 - 3 minutesmins - By Helen Albert

microfluidics cell therapy gene therapy microfluidX

News and Trends 24 Apr 2020

UK Startup to Manufacture Cell and Gene Therapies with Microfluidics

The UK company MicrofluidX has closed a €1.6M (£1.4 M) seed funding round to develop a microfluidic platform that could produce cell and gene therapies more cheaply than conventional cell cultures. The funding round was led by UKI2S, a national seed investment fund targeting early-stage companies, as well as Longwall Ventures and Cambridge Angels. MicrofluidX […]

April 24, 2020 - 3 minutesmins - By David Kirk

txcell car treg organ transplantation

News and Trends 23 Apr 2020

Mogrify Teams Up With Sangamo To Streamline Cell Immunotherapies

The UK cell conversion startup Mogrify and the US genomic medicine company Sangamo have reached an exclusive license agreement that could allow Sangamo to scale up the production of off-the-shelf Treg cell therapies for inflammatory and autoimmune diseases. Under the terms of the agreement, Mogrify will receive an undisclosed upfront payment from Sangamo and will […]

April 23, 2020 - 3 minutesmins - By Laura Cowen

cell therapy manufacturing avectas

News and Trends 16 Apr 2020

Irish Biotech Raises €18M to Develop Non-Viral Cell Therapy Technology

The Irish company Avectas has closed a Series C round to develop cell therapies that don’t need viral vectors — a common bottleneck in cell therapy manufacturing. The fundraise of approximately €18M brings Avectas’ total equity funding to around €37M. The round was led by the company’s current shareholders, which include the serial life sciences […]

April 16, 2020 - 2 minutesmins - By Jonathan Smith

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london ori biotech cell therapy manufacturing

Startup Scout 28 Feb 2020

This Startup Is Automating the Manufacture of Gene and Cell Therapies

In London, the firm Ori Biotech is developing an automated way to manufacture gene and cell therapies, a bottleneck for many biotech companies. Mission: To develop a robotic system to automate the labor-intensive tasks involved in manufacturing cell and gene therapies, such as gene transduction and cell expansion. Gene and cell therapies are maturing as […]

February 28, 2020 - 3 minutesmins - By Jonathan Smith

tcr therapy solid tumor immatics gsk

News and Trends 20 Feb 2020

Immatics Partners GSK in Deal Worth €1B to Develop Cancer Therapies

The German biotech Immatics will partner with GSK and could receive more than €1B from the big pharma for developing cancer immunotherapies based on engineered immune T-cells. Immatics will collaborate with GSK to develop two T-cell therapies that express a protein engineered to detect cancer antigens and kill cancer cells. In return, Immatics will receive […]

February 20, 2020 - 3 minutesmins - By Jonathan Smith

cancer vaccine cancer immunotherapy ervaxx

News and Trends 27 Jan 2020

UK Startup Snaps up Potential Universal Cancer Immunotherapy

The cancer vaccine developer Ervaxx has licensed a preclinical-stage ‘universal’ cancer immunotherapy based on the recent discovery of a new strain of immune T-cells at Cardiff University, UK. Last week, a team led by researchers at Cardiff University published research about T-cells capable of hunting a wide range of cancers including leukemia and melanoma. Experiments […]

January 27, 2020 - 2 minutesmins - By Jonathan Smith

tcr therapy cancer immunotherapy

News and Trends 21 Jan 2020

T-Cell Discovery Could Herald Universal Cancer Immunotherapy

An international research team has found a new type of T-cell that could lead to cell immunotherapies able to treat cancers beyond the reach of current CAR T-cell therapies. Market-approved CAR T-cell therapies including Yescarta and Kymriah have revolutionized cancer treatment by modifying immune T-cells to hunt down cancer cells. However, these treatments are only […]

January 21, 2020 - 3 minutesmins - By Jonathan Smith

allogeneic car t cells cellectis 1

News and Trends 15 Jan 2020

Adaptimmune to Take Off-The-Shelf CAR-T to Phase I with Astellas

The UK biotech Adaptimmune Therapeutics has inked a deal worth up to €806M with Japanese Astellas Pharma to complete phase I trials of candidate off-the-shelf T-cell therapies for cancer including CAR T-cell and TCR therapies. According to the deal, Adaptimmune will collaborate with Universal Cells, a subsidiary of Astellas. The partners will aim to identify […]

January 15, 2020 - 2 minutesmins - By Jonathan Smith

Expert Advice 11 Dec 2019

What Makes a Successful Biotech?

How does it feel to have co-developed the most successful drug in the world? This is something Jane Osbourn, now Chair of the Board at UK cell therapy biotech Mogrify, knows only too well. Early in her career, Osbourn was working as a postdoc in Cambridge and was persuaded to join a small, and at […]

December 11, 2019 - 12 minutesmins - By Helen Albert

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