Gene therapy Archives

How to Develop a Robust Viral Safety Strategy for Gene Therapies

Gene therapies offer a promising hope of cure against rare diseases and other diseases like cancer, with over 1,000 ongoing clinical trials. The increasing need for safe and effective gene therapies is emphasizing the importance of viral safety within the viral vector manufacturing process. This will enable meeting global regulatory timelines and providing faster access […]

October 6, 2021 - 8 minutesmins - By Sudha Sundaram

News and Trends 4 Oct 2021

Non-Viral Gene Therapies Get €51M Boost, Though Challenges Remain

Although most gene therapy still relies on non-infectious viral vectors for delivery, a recent venture financing round for the Swiss company Anjarium Biosciences has shone the spotlight on alternative vectors, including lipid nanoparticles and electric pulses. Last month, Anjarium Biosciences raised €51M (CHF55.5M) in a Series A financing round to advance its gene delivery system […]

October 4, 2021 - 5 minutesmins - By Victor Kotsev

News and Trends 12 Jul 2021

Sofinnova Taps into Italian Gene Therapy with Three Seed Financings

The French investor Sofinnova Partners has injected a total of €6M into three Italian gene therapy companies, cementing Italy’s reputation as a European center for cell and gene therapies. Last month, the venture capitalist Sofinnova Partners used its Telethon fund to inject cash into AAVantgarde Bio, Borea Therapeutics, and Alia Therapeutics. The three firms will […]

July 12, 2021 - 5 minutesmins - By Anita Chakraverty

News and Trends 8 Jul 2021

The Top European Biotech Funding Rounds in June

While oncology and psychedelics dominated European biotech’s biggest funding rounds last month, startup seed financing focused more on gene therapy and drug discovery. Last month saw some momentous events for Europe’s biotech heavyweights. GSK paid an impressive €524M ($625M) upfront to co-develop an immuno-oncology candidate with iTeos Therapeutics in Belgium. Meanwhile, the German antibody drug […]

July 8, 2021 - 5 minutesmins - By Jonathan Smith

biotech stock price euronext genmab argenx

News and Trends 25 May 2021

Delayed IPOs and Market Drops Batter Biotech Stocks

Stock markets worldwide have experienced painful instability in the last few months. As a result, the European biotech market has seen stock prices falling and IPOs postponed. The Covid-19 pandemic was a major disruption for stock markets across the globe at the start of 2020. However, markets like Euronext and the tech-focused Nasdaq rallied and […]

May 25, 2021 - 6 minutesmins - By Jonathan Smith

News and Trends 4 May 2021

Bluebird Bio Withdrawal Raises Gene Therapy Doubts in Europe

Last month, the US firm bluebird bio abandoned the sale of its gene therapy Zynteglo in Germany after a pricing dispute with health authorities — a blow that could have repercussions for the rollout of other gene therapies in Europe. Zynteglo was approved in the EU in 2019 as the first-ever gene therapy for the […]

May 4, 2021 - 5 minutesmins - By Anita Chakraverty

News and Trends 25 Mar 2021

Covid-19 Vaccine Approvals Bring Hope and Challenges for Adenoviral Technology

The rise of adenoviral Covid-19 vaccines highlights the potential of companies using similar technology in other fields like cancer or gene therapy. However, complex challenges remain, such as circumventing immunity to adenoviral treatments. Earlier this month, Johnson & Johnson’s candidate became the first single-shot Covid-19 vaccine to get the EMA green light. The vaccine is […]

March 25, 2021 - 6 minutesmins - By Victor Kotsev

In Depth 10 Mar 2021

Can Gene Therapy Cure Blindness?

Since the approval of the first gene therapy for blindness, there has been a wave of companies developing gene therapy treatments with the potential to cure different forms of genetic blindness. Luxturna became the first gene therapy for inherited blindness to receive FDA approval back in 2017. About a year later, the therapy was approved […]

March 10, 2021 - 7 minutesmins - By Clara Rodríguez Fernández

In Depth 8 Feb 2021

How Next-Generation Gene Therapy Tackles Complex Diseases

Gene therapy has traditionally been applied to well-understood diseases where a single genetic mutation was to blame. A new generation of technology is expanding the potential of gene therapy to treat conditions that were previously unreachable. Since the first gene therapy clinical trials in the 1990s, the technology has made its way into the market […]

February 8, 2021 - 8 minutesmins - By Clara Rodríguez Fernández

Best in Biotech 28 Dec 2020

A Year to Remember: The Biggest European Biotech News in 2020

The Covid-19 pandemic caused huge disruption for European biotech in 2020, but the industry pulled through. Let’s look back at some of the top moments in the last 12 months. After the many drug approvals, startup foundations, and venture capital highs we saw in 2019, it looked like 2020 was going to be a comfortable […]

December 28, 2020 - 12 minutesmins - By Jonathan Smith

In Depth 21 Dec 2020

Enemy or Valuable Ally? How Biotech Uses Viruses for Good

Taking advantage of the ability of viruses to manipulate life is opening new doors for the biotech industry. Once only seen as our enemies, viruses are fast becoming some of our most valuable allies. Viruses may not have the best public image, but to biotechnologists, there’s a lot to admire about them. These tiny molecular […]

December 21, 2020 - 7 minutesmins - By Farhan Mitha

In Depth 4 Nov 2020

The Return of Gene Therapy

Gene therapy is a hot area in the biotech industry right now, with many treatments in development and a number of recent approvals. However, the path has not always been a smooth one. Gene therapy has been one of the biggest success stories of the 21st century. Genetic diseases were once seen as incurable, etched […]

November 4, 2020 - 8 minutesmins - By Farhan Mitha

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