Research Archives

News and Trends 16 Feb 2023

Genetic study reveals high variation in T-cell receptor genes

T-cells are central in the protection against infections and cancer. With the help of TCRs (T-cell receptors), cells recognize foreign invaders and tumor cells. “It was previously unknown how variable human TCR genes are,” said Gunilla Karlsson Hedestam, professor at the department of microbiology, tumor and cell biology at Karolinska Institutet in Sweden, and the […]

February 16, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 16 Feb 2023

Lipid fingerprint could help TB treatment

A new method that measures the amounts of drugs and lipids in individual cells could help health professionals target more effective treatments for diseases such as tuberculosis (TB). Researchers from the University of Surrey in the U.K. were able to isolate individual living cells that contained drugs commonly used to treat tuberculosis and found that […]

February 16, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 9 Feb 2023

New method to design new peptide therapeutics

Researchers at Hokkaido University in Japan have developed a novel method to design and develop peptide antibiotics in large numbers, which could prove critical to controlling antibiotic resistance. Applications of new molecules as drugs are expected to be effective in treating diseases that are difficult to cure with currently used conventional drugs. Peptides are one […]

February 9, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 7 Feb 2023

Antibody candidate for treating serious liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases. However, a new study led by researchers from Karolinska Institutet in Sweden has identified a drug candidate for the treatment of fatty liver. The preclinical study, published […]

February 7, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 7 Feb 2023

Mnemo Therapeutics and Institut Curie studies lead to cancer-specific targets

Mnemo Therapeutics, a French biotechnology company developing immunotherapies, has announced publication of two scientific studies developed at Institut Curie, its closest academic collaborator, in the journal Science Immunology. The publications reveal TE-exon splicing junctions act as a source of novel recurrent, cancer-specific targets and have potential implications for developing more effective and less toxic immunotherapies. […]

February 7, 2023 - 3 minutesmins - By Jim Cornall

Opinion 3 Feb 2023

AI and experiments: new possibilities emerge in 2023

By Markus Gershater, co-founder and chief scientific officer, Synthace The buzz surrounding generative AI has reached fever pitch. It’s a technology so unique and fascinating that the breadth of possibility has done that rare thing of exciting both consumer and business imaginations at the same time. It’s not hard to see why. In the life […]

February 3, 2023 - 5 minutesmins - By External Contributor

News and Trends 3 Feb 2023

AI boosts genome editing

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options. Unintentional errors in the correction of DNA mutations of genetic diseases can thus be reduced. Genome editing technologies offer great opportunities for treating genetic diseases. Methods such as the widely used […]

February 3, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 2 Feb 2023

Possible drug targets from Korean atherosclerosis research

Research suggests that the enzyme phosphoenolpyruvate carboxykinase 2 (PCK2) and its gene play a role in the development of vascular injury and atherosclerosis. Atherosclerosis is a deadly disease; research suggests that proliferation of vascular smooth muscle cells (VSMCs) and formation of a neointimal layer along the inner lining of arteries play a major role in […]

February 2, 2023 - 3 minutesmins - By Jim Cornall

In Depth 1 Feb 2023

Cancer: what are the barriers to research?

Everyone imagines a world without cancer, but getting there is difficult. With World Cancer Day coming up on February 4, we took the opportunity to ask some life science company CEOs, CMOs, and chief scientific officers the same question about cancer research. We asked CellCentric CEO, Will West; iOnctura CEO, Catherine Pickering; ISA Pharmaceuticals chief […]

February 1, 2023 - 6 minutesmins - By Jim Cornall

Opinion 1 Feb 2023

Computational chemistry and cancer

by Martin Slater, Cresset Discovery Computational chemistry offers a fast and innovative approach to drug discovery and is especially powerful when used in combination with biological testing to provide a complete and reliable picture of a target system. This is perhaps no better illustrated than in Cresset Discovery’s project with University of South Australia, which […]

February 1, 2023 - 3 minutesmins - By External Contributor

News and Trends 31 Jan 2023

The next breakthrough in cancer treatment?

In our body, we have an innate immune system and an immune system that is developed throughout life. Part of the innate immune system consists of so-called NK (natural killer) cells. This is a type of immune cell that specializes in killing cancer cells. These cells may be of great importance for cancer treatment in […]

January 31, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 31 Jan 2023

Singapore researchers use old drug as new acute leukemia treatment

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, has revisited an existing drug to combat a type of blood cancer called T-cell acute lymphoblastic leukemia, or T-ALL. The research was led by Takaomi Sanda and Lim Fang Qi. The drug, PIK-75, was initially discovered […]

January 31, 2023 - 4 minutesmins - By Jim Cornall

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