Research Archives

Podcast 25 Aug 2023

Beyond Biotech podcast 60 – The cost of research

On this week’s podcast, we have a conversation with Dr Jack Scannell, CEO of Etheros Pharmaceuticals Corp. Scannell recently co-authored a paper on the expenses related to clinical research and the factors that underly the translational failure of inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) in oncology. Costs and Causes of Oncology Drug Attrition […]

August 25, 2023

In Depth 22 Aug 2023

Lab-grown babies on the horizon: how IVG could transform human reproduction

Lately, there seems to have been a lot of talk about the possibility of ‘lab-grown babies’. Proper research into this area kicked off around a decade ago, and is still largely experimental in humans. But the technique used to potentially develop lab-grown babies could hold the power to provide a novel treatment option for human […]

August 22, 2023 - 8 minutesmins - By Willow Shah-Neville

News and Trends 28 Jul 2023

Could a natural sweetener from hydrangeas treat Alzheimer’s disease?

Amyloid β (Aβ) aggregation is primarily responsible for the development of Alzheimer’s disease (AD). In a new mouse model study, South Korean researchers investigated the effect of phyllodulcin — a natural sweetener found in the hydrangea plant — in inhibiting Aβ accumulation. The results suggest that phyllodulcin effectively inhibits Aβ accumulation and decomposes the pre-aggregated […]

July 28, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 26 Jul 2023

Diabetes drug could promote healthy aging

A research team from the School of Public Health, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has provided genetic evidence that metformin might promote healthy aging using a cohort study of more than 300,000 participants of European descent (UK Biobank). The proof-of-concept work supports further clinical research into the drug repositioning […]

July 26, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 25 Jul 2023

Can the microbiome help the fight against infections?

Animals and humans coexist with a vast array of microorganisms known as the microbiome, forming a relationship that can range from mutually beneficial to pathogenic. To safeguard against harmful pathogens and maintain the presence of beneficial microorganisms, animals have evolved various defenses.One is small antimicrobial peptides (AMPs), small peptides that combat invading microbes. AMPs are […]

July 25, 2023 - 4 minutesmins - By Jim Cornall

In Depth 21 Jul 2023

How AI is shaping clinical research and trials

Artificial intelligence (AI) is everywhere at the minute, seemingly being used in some capacity in almost every professional industry, including clinical research and trials. In fact, it is fair to say that AI has taken the biotech industry by storm, and the hype surrounding it has led to numerous AI startup companies coming onto the […]

July 21, 2023 - 7 minutesmins - By Willow Shah-Neville

News and Trends 20 Jul 2023

CatalYm shows importance of GDF-15 in tumor immunotherapy resistance

CatalYm has published preclinical data in Nature Communications that reveal the central role of Growth Differentiation Factor-15 (GDF-15) in the resistance of tumors to current immunotherapy. CatalYm said the findings further highlight the therapeutic significance of its proprietary anti-GDF-15 antibody candidate, visugromab, currently in advanced phase 2 clinical studies. The foundational research, which was performed […]

July 20, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 19 Jul 2023

Novel bacterial communication system could help take on antimicrobial resistance

A new stress signaling system enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics. The discovery was made by researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Singapore Centre for Environmental […]

July 19, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 14 Jul 2023

Life saved: AI discovers existing drug works for rare disease

A patient’s life was saved after researchers at the University of Pennsylvania, Castleman Disease Collaborative Network, Medidata, and Every Cure, used artificial intelligence to use an existing drug to treat idiopathic multicentric Castleman disease (iMCD). Every Cure and its partners are developing medical databases and AI algorithms to unlock new uses for existing medicines across […]

July 14, 2023 - 4 minutesmins - By Jim Cornall

Dr. Grégoire Stik, group leader at the Josep Carreras Leukaemia Research Institute and co-author of the study.

News and Trends 11 Jul 2023

Immune memory research could lead to next generation of epigenetic drugs

A team of researchers has discovered that the memory of the immune system relies on characteristic epigenetic features and a specific 3D arrangement of the DNA in the nucleus of memory cells, allowing for a fast activation of these cells. These features are altered in chronic inflammation diseases like asthma and could be important in […]

July 11, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 10 Jul 2023

Existing cancer drug could be repurposed to fight certain aggressive cancers

A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has found that an existing cancer drug could be repurposed to target a subset of cancers that currently lack targeted treatment options and is often associated with poor outcomes.This subset of cancers makes up 15% of all cancers and is especially prevalent in […]

July 10, 2023 - 5 minutesmins - By Jim Cornall

News and Trends 7 Jul 2023

Swedish researchers look to peptides to destroy viruses

A new study from Sweden shows how a type of peptide from a lactic acid bacterium destroys viruses, including coronavirus. The findings have resulted in a Swedish patent, with an international patent pending. “We’re hoping for a quick turnaround to allow this discovery to be utilised in antiviral treatments and as a complement to vaccine,” […]

July 7, 2023 - 3 minutesmins - By Jim Cornall

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