Research Archives

News and Trends 4 Apr 2023

Discovery could lead to cancer drugs with fewer side effects

Many anticancer drugs have serious side-effects in clinical practice. Kinesin inhibitors block kinesin motor proteins required for cancer cell division, and are promising anticancer drug candidates with minimal side-effects. However, their association with kinesin proteins remains unclear. Researchers from Japan have addressed this by solving the crystal structure of the complex formed by the kinesin […]

April 4, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 31 Mar 2023

Candidate found to inhibit malignant melanoma growth

Malignant melanoma is a relatively aggressive type of skin cancer. When detected early, it is usually treatable by surgical resection only, but metastases develop, often spreading to distant areas. Currently, tumor thickness and the presence of ulceration are some of the known prognostic factors used as indicators of melanoma. Therefore, the discovery of markers to […]

March 31, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 30 Mar 2023

Could new riboswitch make gene therapy safer?

Turning genes on and off as easily and predictably as flicking a switch could be a powerful tool in medicine and biotech. A type of technology called a riboswitch might be the key.The Okinawa Institute of Science and Technology (OIST) in Japan, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses […]

March 30, 2023 - 5 minutesmins - By Jim Cornall

News and Trends 24 Mar 2023

Metabolism of RNA linked to leukemia

Researchers at Lund University Faculty of Medicine in Sweden have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is […]

March 24, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 23 Mar 2023

Gut microbiota to be harnessed as a tool to diagnose diseases

A recent study at the University of Jyväskylä in Finland compared the gut microbiota and gut-derived metabolites between healthy controls and individuals with fatty liver. The results revealed that certain microbial metabolites are associated with liver fat content. The fact that the gut microbiota associates with many diseases has raised the hope that they could […]

March 23, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 23 Mar 2023

Intracellular “smoke detector” discovery has skin disease therapy implications

A study by the University of Bonn in Germany could lead to therapies against skin and intestinal diseases in the medium term.Researchers at the universities of Bonn and Singapore have discovered a new intracellular “smoke detector.” The sensor warns of damage to the mitochondria – the microscopic power plants that supply the cell with energy. […]

March 23, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 17 Mar 2023

How cancer cells repair DNA damage from radiotherapy

A team of scientists led by Kei-ichi Takata from the Center for Genomic Integrity (CGI) within the Institute for Basic Science (IBS) in South Korea, has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy. Ionizing radiation (IR) therapy is frequently used in the treatment […]

March 17, 2023 - 5 minutesmins - By Jim Cornall

Best in Biotech 15 Mar 2023

10 immunotherapy companies making waves in 2023

Immunotherapy has been widely studied in cancer treatment research, ever since William Coley, who is regarded as the father of immunotherapy, first attempted to leverage the immune system for oncological therapy in 1891. Soon enough, the transformative power of cancer vaccines were observed where tumor-specific antigens triggered antitumor immune responses. Along with these technological advancements, […]

March 15, 2023 - 10 minutesmins - By Roohi Mariam Peter

Expert Advice 14 Mar 2023

5 reasons why collaboration is important in research

In the life sciences industry, collaboration is paramount in the field of research, to help move ideas and programs forward through the various stages. Here, experts explain the importance of research collaboration for biotechs. Collaboration in research is critical for the long-term success of biotechs, and going it alone is rarely a feasible option, particularly […]

March 14, 2023 - 7 minutesmins - By Willow Shah-Neville

News and Trends 14 Mar 2023

How the microbiome can predict cancer immunotherapy success

A new study shows antibiotic treatment prior to CAR-T cell therapy is connected to unfavorable treatment outcomes. An international team headed by Eran Elinav of the Cancer & Microbiome Division of the German Cancer Research Center (DKFZ), and led by Christoph Stein-Thoeringer, professor of Clinical Infectiology and Translational Microbiome Research at the Medical Faculty of […]

March 14, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 9 Mar 2023

Twisted blood vessels reveal cancer treatment success potential

Picture Health has announced plans to commercialize a new artificial intelligence (AI)-powered biomarker with the potential to transform the way doctors decide how to treat cancer. The advancement in cancer outcomes research sheds new light on cancer tumors: analyzing the state of the blood vessels that feed them. Recently published studies have shown the technology […]

March 9, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 9 Mar 2023

Researchers develop treatment for vancomycin-resistant bacteria

Researchers from several institutions have developed a treatment for bacteria resistant to vancomycin, which is also known as vancomycin-resistant Enterococcus faecalis (VRE). The group consists of researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Singapore Centre for […]

March 9, 2023 - 4 minutesmins - By Jim Cornall

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