RNA technology Archives

News and Trends 31 Oct 2022

Scientists say RNA production inhibitors important in cancer research

A study by researchers at the Biomedical Institute of Seville (IBIS) and the University of Seville, in collaboration with the Danish Cancer Society, shows that inhibiting RNA synthesis after radiation therapy facilitates the death of tumor cells. The study was published in the journal Nature Communications. RNA has been shown to be essential for repairing […]

October 31, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 12 Oct 2022

SiSaf takes steps with FDA for RNA therapeutic to treat rare genetic skeletal disorders

SiSaf Ltd, an RNA delivery and therapeutics company, is initiating the U.S. FDA Regulatory process to obtain orphan drug designation for SIS-101-ADO. SIS-101-ADO is a siRNA therapeutic for patients with autosomal dominant osteopetrosis type 2 (ADO2), a rare genetic skeletal disorder. The request for orphan drug designation and advancement through the regulatory process that SIS-101-ADO […]

October 12, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 12 Oct 2022

Ascidian Therapeutics launches with $50M to rewrite RNA

Ascidian Therapeutics, a biotechnology company focused on treating human diseases by rewriting RNA, has been launched. With an initial focus on replacing mutated exons at the RNA level, Ascidian’s technology enables therapeutic targeting of large genes and genes with high mutational variance while maintaining native gene expression patterns and levels. This approach is designed to […]

October 12, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 7 Oct 2022

Ziphius and UZ Ghent collaborating on manufacture of saRNA-based vaccines

Ziphius Vaccines, a biopharmaceutical company developing vaccines and therapeutics based on self-amplifying RNA (saRNA), and UZ Ghent have entered a public-private collaboration for the scale up and manufacturing of prophylactic self-amplifying RNA vaccines based on GMP (good manufacturing practice) standards. The collaboration is a first in Europe where a university hospital produces GMP grade prophylactic […]

October 7, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 20 Sep 2022

Regen BioPharma files patent on new RNA/DNA-based approach to cancer immunotherapy

Regen BioPharma, Inc. has filed a provisional patent application with the USPTO entitled “Dual Checkpoint Inhibitor Aptamer Based Therapeutics.” The application covers novel compositions of matter capable of acting as conventional checkpoint inhibitor drugs while simultaneously silencing genes that regulate T cells and cancer cells such as NR2F6 and Survivin. The company says this platform […]

September 20, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 19 Sep 2022

Global consortium looks to develop breakthrough RNA-based anti-cancer immunotherapy

The Hadassah Cancer Research Institute (HCRI) at the Hadassah University Medical Center in Jerusalem, Israel, is to lead CanceRNA, a global consortium aiming to apply RNA-based therapeutics to successfully unlock anti-cancer immune responses. While RNA-based therapies, namely mRNA vaccines, shone during the pandemic and saved millions of lives, they have yet to be successfully tested […]

September 19, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 12 Sep 2022

SiSaf reveals positive preclinical data in siRNA program to treat osteopetrosis

SiSaf Ltd, an RNA delivery and therapeutics company, has announced positive data confirming safety and efficacy of its Bio-Courier next generation silicon stabilized hybrid lipid nanoparticles (sshLNP) as an effective non-viral delivery system for autosomal dominant osteopetrosis type 2 (ADO2) siRNA therapy. The data was presented at the American Society of Bone and Mineral Research […]

September 12, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 7 Sep 2022

Benchling launches solution to boost mRNA and RNA therapeutics development

Benchling has launched what it says is the industry’s first full set of capabilities for designing, modeling, and studying natural and chemically modified RNA in a single solution. As the biopharma industry increases its focus on developing RNA therapeutics, Benchling said its new RNA solution is the first purpose-built offering on the market to help […]

September 7, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 24 Aug 2022

Gene therapies for lung cancer identified by international team of scientists

Gene therapies for lung cancer can be found by CRISPR genome editing technology, an international team of scientists have discovered. CRISPR genome-editing is a powerful tool that gives scientists a cheap and easy way to find and alter a specific piece of DNA within a cell – the ‘cut and paste’ of the biological world. […]

August 24, 2022 - 2 minutesmins - By Liza Laws

News and Trends 17 Aug 2022

AUM LifeTech secures $400,000 grant for lung cancer immunotherapy program

AUM LifeTech, Inc., a Philadelphia-based preclinical stage biotech company, has received a Small Business Innovation Research (SBIR) grant from the National Cancer Institute (NCI) of the National Institutes of Health (NIH) to advance its preclinical program in lung cancer immunotherapy using a non-viral RNA-targeting gene therapy approach. “This grant will help advance our preclinical immunotherapy […]

August 17, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 3 Aug 2022

siRNA company Eleven Therapeutics seals $22M funding

Eleven Therapeutics has raised a total of $22 million in seed funding. Among the roster of funders is the Bill & Melinda Gates Foundation, which committed $9 million in funding to Eleven, including $5 million towards future equity investment supporting the development of a first-of-its-kind platform that designs small interfering RNAs (siRNAs) with ultra-long durability […]

August 3, 2022 - 3 minutesmins - By Jim Cornall

In Depth 22 Jul 2022

The coming of age story of RNAi technology

The first RNA interference (RNAi) therapy was approved in 2018, after 20 years in development. What can we expect to see in the RNAi field in the future? After two decades of scientific effort, multiple devastating clinical trial setbacks, and billions of dollars spent on research and development, RNAi therapies are finally establishing themselves in […]

July 22, 2022 - 7 minutesmins - By Farhan Mitha

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