RNA technology Archives

News and Trends 6 Jan 2020

BioNTech’s RNA-Boosted CAR T-Cell Therapy Shrinks Tumors in Mice

A CAR T-cell therapy amplified by RNA technology, developed by BioNTech, has shown preclinical potential for tackling solid tumors, which are hard to treat with current CAR T-cell therapies. In a study published in Science, the CAR T-cell and RNA combination therapy suppressed tumors in mice implanted with human ovarian cancer for longer than regular […]

January 6, 2020 - 2 minutesmins - By Jonathan Smith

Best in Biotech 30 Dec 2019

European Biotech’s Top News in 2019

With the year coming to a close, it’s time to review the most important biotech news events that took place in the European biotech industry in 2019. It has been a solid year for the European biotech industry. In 2019, venture capital funding in Europe continued to be high after a very good year in […]

December 30, 2019 - 10 minutesmins - By Jonathan Smith

News and Trends 25 Nov 2019

Novartis Enters RNA Therapeutics with Medicines Company Merger

Novartis is to acquire The Medicines Company and its late-stage RNA interference drug designed to protect against cardiovascular disease in twice-yearly shots. Novartis will pay €8.8B ($9.7B) to acquire The Medicines Company, which is based in the US and focuses on developing the RNA drug inclisiran for the treatment of cardiovascular disease and renal impairment. […]

November 25, 2019 - 3 minutesmins - By Jonathan Smith

More News! 11 Oct 2019

RNA Therapy Improves Vision in Untreatable Genetic Blindness

A phase I/II trial run by the Dutch company ProQR has found that its RNA therapy could significantly improve the vision of people with Leber’s congenital amaurosis, a rare genetic disease for which there is no treatment. The RNA drug, called sepofarsen, is designed to treat people with a specific mutation in a gene […]

October 11, 2019 - 3 minutesmins - By Clara Rodríguez Fernández

Interview 3 Jul 2019

Meet the First Company in the Brand New Field of Epitranscriptomics

A whole new therapeutic area is taking medical research by storm. In Cambridge, UK, the company Storm Therapeutics is leading the development of the first treatments to target a new layer of genetic information encoded in the RNA. The term ‘epitranscriptomics’ did not exist a decade ago. It was coined in 2012, when scientists started […]

July 3, 2019 - 5 minutesmins - By Clara Rodríguez Fernández

News and Trends 20 May 2019

Update: British RNA Biotech Increases Series A to €34M

Update (20/05/19): Storm Therapeutics has increased its series A financing round by an additional €16M (£14M) to €34M (£30M), which the company plans to use to advance its pipeline of RNA focused drug candidates towards the clinic. Seroba Life Sciences, an Irish VC focusing on new and innovative therapies, is the key new investor. Existing […]

May 20, 2019 - 2 minutesmins - By Helen Albert

celixir rnai silencing cancer colon breast

News and Trends 14 May 2019

RNAi Therapy Smashes Solid Tumors in Preclinical Tests

Developed by the UK biotech Celixir, a therapy based on silencing genes with RNA molecules in a process called RNAi has shrunk tumors by 50% in culture. Although there are lots of innovative cancer treatments in the market, such as CAR T-cell therapy for blood cancer, solid tumors remain difficult to tackle. For this reason, […]

May 14, 2019 - 2 minutesmins - By Jonathan Smith

Best in Biotech 28 Jan 2019

5 Real-Life Technologies Where Biotech Meets Science Fiction

From genetic engineering to synthetic food and immortality, biotech is getting surprisingly close to recreating science fiction in real life. Science fiction is always a step ahead of real-life science. The genre imagined space travel, wireless communication and virtual reality years before they became a reality. In fact, sci-fi has coined some scientific terms […]

January 28, 2019 - 6 minutesmins - By Clara Rodríguez Fernández

alnylam silence therapeutics lawsuit settlement

News and Trends 11 Dec 2018

UK Biotech Settles Lawsuit on the First RNAi Drug

Silence Therapeutics and Alnylam have reached a settlement that puts an end to a legal dispute between them resulting in Silence receiving some royalties on Onpattro, the first RNA interference drug. The lawsuit started last year, when Silence went to the UK courts claiming that Alnylam was infringing on its intellectual property. As part of […]

December 11, 2018 - 3 minutesmins - By Clara Rodríguez Fernández

News and Trends 20 Sep 2018

RNA Therapy Shows Promise for Treating Liver Cancer

British biotech MiNA Therapeutics’ innovative RNA treatment may enhance liver cancer patients’ response to standard cancer therapies, suggest early results from a Phase I/IIa clinical trial. When they received the biotech’s small activating RNA (saRNA) treatment, two patients showed complete responses after being given the cancer treatment sorafenib and one showed a partial response to […]

September 20, 2018 - 2 minutesmins - By Jonathan Smith

News and Trends 5 Sep 2018

RNA Therapy Improves Vision in Patients with Rare Genetic Blindness

Dutch company ProQR has released data from a Phase I/II trial showing its RNA therapy can improve the vision of people with a rare form of hereditary blindness. The clinical trial recruited 10 people with the rare disease Leber’s congenital amaurosis 10. Caused by mutations in a gene called CEP290, this condition leads to […]

September 5, 2018 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 30 Aug 2018

First RNAi Drug Approved in Europe After 20 Years of Research

The first ever RNA interference (RNAi) drug, used to treat polyneuropathy in patients with hereditary transthyretin-mediated amyloidosis, has been given marketing approval by the European Commision. The approval follows that of the US FDA who gave the green light to US biotech Alnylam Pharmaceutical’s Onpattro (patisiran) earlier this month following positive Phase III findings in […]

August 30, 2018 - 3 minutesmins - By Helen Albert

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