CAR-T therapies have gained plenty of attention lately by promising to end cancer with a one-off treatment. But all that glitters is not gold; experts remind us it is important to be critical about the immuno-oncology hype.
Immuno-oncology has become all the rage lately, and the hype has led to some major investments, acquisitions, deals and partnerships. It seems that the label “immuno-oncology” is sufficient to increase the value of the product. But Dr. Philip Greenberg, cofounder of Juno Therapeutics, a big Biotech developing CAR-T therapies, has called attention to the many challenges this field faces.
The first attempts to stimulate T-cells to attack tumors got the attention of big Pharma like Novartis, Kite Pharma and Juno Therapeutics. These companies are now advancing their programs in CAR-T, the breakthrough therapy that everyone’s after. In this treatment, the patient’s T-cells are engineered in vitro,