A package of four landmark papers were published yesterday in the online edition of Nature Genetics. The research, written by a team of deCODE scientists, was built on whole-genome sequence data from more than 100,000 people from across Iceland. The four milestone studies together present the most detailed portrait of a population yet assembled using the latest technology for reading DNA.
The studies are built around the most comprehensive population-wide tally to date of sequence variation, authored by a team of deCODE scientists led by Dr. Kari Stefansson, deCODE’s founder and CEO. They provide the largest and most detailed set of common as well as rare allele frequencies, critical for advancing more efficient diagnostics; a population-wide collection of human knockouts; and new risk factors for Alzheimer’s and a range of other diseases.
Dr. Kari Stefansson said: “This work is a demonstration of the unique power sequencing gives us for learning more about the history of our species and for contributing to new means of diagnosing,