Italy Archives

News and Trends 17 Oct 2022

Italian study shows CRISPR/Cas9 deletion of Interleukin-30 reduces prostate cancer growth

Metastatic prostate cancer is a leading cause of cancer death in men worldwide. Interleukin (IL)-30, a cytokine that may perform immunomodulatory functions, promotes prostate cancer onset and development, but whether it can be a suitable therapeutic target remains to be investigated. In a new study published in the Journal of Hematology & Oncology, researchers at […]

October 17, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 12 Sep 2022

Reveal Genomics reveals more HER2DX breast cancer validation data

Reveal Genomics, S.L. says it has received more validation of HER2DX, the world’s first specialized genomic test for HER2+ breast cancer. Valentina Guarneri from the University of Padova presented the data at the European Society of Medical Oncology Congress 2022 in Paris, France. The data obtained from the analysis of tumor samples from the PerELISA […]

September 12, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 22 Aug 2022

Santhera and ReveraGen announce first patient with Becker muscular dystrophy dosed in FDA-funded pilot study

The first patient has been dosed in a phase 2 pilot study looking at a treatment for muscular dystrophy. Santhera Pharmaceuticals and ReveraGen BioPharma made the announcement that vamorolone is to be assessed in patients with Becker muscular dystrophy (BMD). The study is being funded by the U.S. Food and Drug Administration (FDA). Eric Hoffman, […]

August 22, 2022 - 3 minutesmins - By Liza Laws

News and Trends 17 Aug 2022

New partnership delivers clinically proven products and manufacturing processes for advanced therapies

AGC Biologics has announced its partnership with supplier of human mesenchymal stem/stromal cells (hMSCs), RoosterBio Inc. The partnership, the companies say creates an end-to-end solution for the development and production of hMSCs and exosome therapeutics using RoosterBio’s well-established cell and media products and process development services together with AGC’s cell and gene therapy manufacturing capabilities. […]

August 17, 2022 - 3 minutesmins - By Liza Laws

News and Trends 28 Jul 2022

AGC Biologics announces gene therapy partnership with Altheia Science

A new development partnership between gene therapy company Altheia Sciences, which pioneers cell and gene treatments, and AGC Biologics, will look at strategies to treat autoimmune disease and cancer. Specifically, the partnership will help advance development of autoimmunity treatments, focused on modulating PD-L1 expression in patients’ hematopoietic stem and progenitor cells, into clinical testing. PD-L1 […]

July 28, 2022 - 2 minutesmins - By Liza Laws

cardiovascular disease heart attack forcefield therapeutics

News and Trends 25 Apr 2022

Forcefield Therapeutics Launched to Treat Heart Attacks with Protein Drugs

The startup Forcefield Therapeutics has been unveiled in the UK with €6M (£5.5M) backing from the investment firm Syncona. The mission is to develop the first drugs to safeguard heart muscle from damage during heart attacks. A sudden heart attack, also known as acute myocardial infarction, happens when the flow of blood to the heart […]

April 25, 2022 - 4 minutesmins - By Jonathan Smith

Gene therapy genenta science genflow biosciences

News and Trends 21 Jan 2022

Two Gene Therapy Players Launch IPOs on Stormy Stock Market

After a drought of more than a year, the European gene therapy sector saw initial public offerings from Genenta Science and Genflow Biosciences. The firms aim to shine as biotech stocks elsewhere perform poorly. Until recently, European gene therapy companies were going through a dry spell in terms of launching initial public offerings (IPO). The […]

January 21, 2022 - 4 minutesmins - By Jonathan Smith

News and Trends 19 Jan 2022

Engitix Builds Liver Disease Pipeline with Series A and Drug Collaboration

With the close of its Series A round at €48M ($54M), the tissue models company Engitix has shifted its business from providing drug discovery services to developing its own treatment pipeline for liver diseases. When Engitix was spun out of University College London in 2016, the startup primarily aimed to provide tissue models to pharmaceutical […]

January 19, 2022 - 3 minutesmins - By Jonathan Smith

News and Trends 12 Jul 2021

Sofinnova Taps into Italian Gene Therapy with Three Seed Financings

The French investor Sofinnova Partners has injected a total of €6M into three Italian gene therapy companies, cementing Italy’s reputation as a European center for cell and gene therapies. Last month, the venture capitalist Sofinnova Partners used its Telethon fund to inject cash into AAVantgarde Bio, Borea Therapeutics, and Alia Therapeutics. The three firms will […]

July 12, 2021 - 5 minutesmins - By Anita Chakraverty

News and Trends 28 Jul 2020

Record Series A for Italian Biotech Funds Autoimmune Therapy

Italian biotech Enthera raised €28M in Series A funding to develop its drug candidate for type 1 diabetes and inflammatory bowel disease and take it to human trials. Enthera was founded in 2016 and is the first company to ‘graduate’ from the BiovelocITA accelerator program in Milan, which is supported by French life science investor […]

July 28, 2020 - 3 minutesmins - By Helen Albert

pharma mediolanum farmaceutici menarini elsalys stemline

News and Trends 11 May 2020

Italian Pharma Getting Back to Normal With Two Biotech Acquisitions

Despite the country being hard hit with Covid-19, Italian pharma seems to be getting back to business as usual with two oncology-related biotech acquisitions in the last week. The most recent acquisition was of French immuno-oncology company ElsaLys Biotech by Mediolanum Farmaceutici, a pharmaceutical group based in Milan. The French biotech has several candidate drugs […]

May 11, 2020 - 4 minutesmins - By Helen Albert

Orchard therapeutics gene therapy header

News and Trends 23 Apr 2020

Sofinnova Invests €20M in Three Italian Rare Disease Biotechs

The French VC firm Sofinnova Partners has invested €20M in three Italian biotech companies via its Telethon Fund, which focuses on firms developing treatments for rare diseases. The deals by the Sofinnova Telethon Fund were made over the last several months. The companies the Fund invested in — Genespire, Epsilen Bio, and PinCell — are […]

April 23, 2020 - 3 minutesmins - By Jonathan Smith

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