Will SynBio replace the French Wine Industry? By Clara Rodríguez Fernández 3 minutesmins October 7, 2016 -Updated: onJune 22, 2022 3 minutesmins Share WhatsApp Twitter Linkedin Email Newsletter Signup - Under Article / In Page"*" indicates required fieldsPhoneThis field is for validation purposes and should be left unchanged.Subscribe to our newsletter to get the latest biotech news!By clicking this I agree to receive Labiotech's newsletter and understand that my personal data will be processed according to the Privacy Policy.*Company name*Job title*Business email* Ava Winery is creating cheap, sustainable and customizable wine without grapes, yeast or fermentation. The company plans to commercialize its first product in the coming months, will they be able to steal customers from the most famous French wine companies?Ava Winery claims that 90% of tasters cannot tell its prototype apart from traditional wine. The US start-up raised €2.42M ($2.7M) in August in a round led by Hong-Kong giant Horizon Ventures to perfect the product. The plan is to start commercialization in the next 6 to 12 months and the first bottles are already available for pre-order.The idea behind this company is simple: wine is just a mixture of chemicals (water, sugars, alcohol, organic volatiles, flavonoids…), and therefore can be made putting these components together. The concept started out as a home experiment and now counts with high-tech chromatography equipment to help identify wine components.But why develop a new method of making wine? The fanciest of the beverages can reach prices higher than €10,000, which means most of us will never be able to taste them. However, this new technology saves time and money and can potentially replicate any wine. In fact, the founders claim their technology could be used to explore what makes a wine great and create a whole-new range of flavors.Even better, this process uses 50 to 100 times less water and does not require the exploitation of huge plantation areas. And since the product is made from sterilized components it won’t go bad.Figure 1. Ava Winery plans to create wine from scratch by mixing its main componentsHowever, the company still has a long way to go. Its investment funds will go into developing methods to quantify the complex molecular mixtures of wine. Tuning the precise amounts of each of the hundred components that interact with each other in a wine is an essential step to improve the flavor.But the main challenges are further downstream; the product needs to achieve wine classification from regulatory agencies and the marketing strategy could prove tough. Though the concept is great, some people might be reluctant to substitute their favorite wine for a lab-made version. The company might be competing with Replica Wine, which also recreates great wines with cheap alternatives, though still using old-fashioned grape fermentation.Ava Winery is another food-tech SynBio company, much like Perfect Day (previously Muufri), a start-up that makes cow milk without the cows. SynBio is trying to revolutionize the way we approach food: the development of technologies that reduce the huge environmental impact of agricultural practices is currently one of the main challenges of our growing population.Could these alternatives truly replace the best traditional wines one day? Can they really match the flavor and texture? Or will our love for tradition make us settle for the original? We might have some answers soon when the products reach the market.Partnering 2030: FME Industries Report Which food, material, and electromechanical industry companies are perceived most highly by research institutes? Which partnering channels work best? What do institutes want from industry partners? Download the report Explore other topics: SustainabilitySynthetic biology ADVERTISEMENT