For any drug developer or service provider, cell line development is one of the most challenging phases, especially when subsequent GMP compliance is required. The need to secure good cell lines can, therefore, make all the difference in getting any biological to the market.
The Swiss company Celonic has produced CHOvolution™, a cell line kit that allows you to develop your own mammalian cell lines with an integrated support system to help.
The CHOvolution™ is built on a highly robust and efficient technology that not only adds economic value to your project early on but assures the development success from discovery to market.
Why use cell lines?
Mammalian cells provide a great advantage for the R&D stage of a therapeutic antibody’s development due to the similarity of the cells to human cells (e.g. folding, glycosylation etc). For example, CHO-K1-based cell lines, derived from the ovarian cells of the Chinese hamster, have become a standard for the production of therapeutic proteins.