News and Trends 31 Jan 2020 AI-Designed Drug Enters Phase I to Treat OCD A drug designed by the UK firm Exscientia using AI-powered software has entered into a phase I clinical trial for the treatment of obsessive-compulsive disorder, commonly known as OCD. The clinical development of the drug will be carried out by Sumitomo Dainippon Pharma, Exscientia’s Japanese collaborator. The drug took just 12 months to get to […] January 31, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 31 Jan 2020 This Cancer Immunotherapy Attacks the Sugar Coat of Tumor Cells The Portuguese company CellmAbs is developing cancer immunotherapies that prevent tumor cells from evading the immune system by hitting sugar molecules on their surface. Mission: To develop drugs that bind with a type of sugar molecules only found on the surface of cancer cells called aberrant glycans. Some of these aberrant glycans are able to […] January 31, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 30 Jan 2020 Austrian Genomics Company Joins Fight Against Coronavirus Ares Genetics will use next-generation sequencing technology from the Chinese genomics company BGI Group to track and control the spread of a new coronavirus originating in China. A new strain of coronavirus, dubbed 2019-nCoV and originating in the Chinese city of Wuhan, has caused widespread concern in recent weeks. While only 20% of people with […] January 30, 2020 - 2 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 29 Jan 2020 Oxitec Unveils First Field Trial Results for Crop-Protecting GM Moths A study led by Oxitec has shown for the first time that diamondback moths genetically engineered to produce only male offspring can survive in the wild, a solution that shows promise for cutting populations of the crop pest. Caterpillars of the diamondback moth Plutella xylostella are one of the most destructive pests for growers of […] January 29, 2020 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 28 Jan 2020 A Future Gene Therapy Could Be Delivered in Tiny ‘Nanocontainers’ A Swiss research group has developed tiny plastic particles that could carry gene therapies to the center of the cell with less risk of getting attacked by the immune system than conventional gene therapies. The majority of gene therapies in use today are delivered to the DNA of target cells using viral vectors. While efficient […] January 28, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 27 Jan 2020 UK Startup Snaps up Potential Universal Cancer Immunotherapy The cancer vaccine developer Ervaxx has licensed a preclinical-stage ‘universal’ cancer immunotherapy based on the recent discovery of a new strain of immune T-cells at Cardiff University, UK. Last week, a team led by researchers at Cardiff University published research about T-cells capable of hunting a wide range of cancers including leukemia and melanoma. Experiments […] January 27, 2020 - 2 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 24 Jan 2020 €6M Seed Round to Develop First Urine Test for Kidney Cancer The Swedish biotech Elypta has raised a seed round worth €6.1M to fund a clinical trial of a urine test for signs of recurrent kidney cancer, which could improve patient follow-up after surgery. The seed round was led by the Swedish VC firm Industrifonden. Other investors in the round included the VC impact fund of […] January 24, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 23 Jan 2020 Merck Spinout Bags €15M Series A to Tackle Cancer and Fibrosis iOnctura, a spinout from Merck KGaA, has raised €15M to take its cancer and fibrosis drugs to phase I clinical trials. The Series A round was co-led by new investors INKEF Capital and VI Partners. The founding investor of iOnctura, M Ventures — the corporate venture arm of Merck — also contributed to the round, […] January 23, 2020 - 2 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 22 Jan 2020 FDA Greenlights First Treatment for Rare Autoimmune Eye Disease An antibody drug developed by the Irish biopharma Horizon Therapeutics has been approved by the FDA for the treatment of adults with the rare autoimmune condition thyroid eye disease. The approval of the drug came ahead of schedule, with the decision originally expected in March. The drug, a monoclonal antibody, is branded as Tepezza. Thyroid […] January 22, 2020 - 2 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 22 Jan 2020 Off-The-Shelf Lung Cancer Vaccine Clinical Trial Gets €20M Boost The French-Belgian company PDC*Line Pharma has raised a €20M Series B round to fund an ongoing phase I/II trial of its off-the-shelf therapeutic vaccine for lung cancer. The total €20M consists of €13.9M in equity investments and €6.1M in loans and subsidies from the Walloon Region of Belgium. PDC*Line’s current investors took part in the […] January 22, 2020 - 2 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
News and Trends 21 Jan 2020 T-Cell Discovery Could Herald Universal Cancer Immunotherapy An international research team has found a new type of T-cell that could lead to cell immunotherapies able to treat cancers beyond the reach of current CAR T-cell therapies. Market-approved CAR T-cell therapies including Yescarta and Kymriah have revolutionized cancer treatment by modifying immune T-cells to hunt down cancer cells. However, these treatments are only […] January 21, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Interview 21 Jan 2020 How Biotech Startups Can Have a Stronger Position When Scaling Up Scaling up the manufacturing process can be a daunting task for any biotech startup. Evelina Vågesjö, CEO of Swedish gene therapy biotech Ilya Pharma, and Jesper Hedberg, Director of the Testa Center facility, explained how testing at innovation facilities such as incubators and biotech accelerators can help avoid big pitfalls in the scaling process later […] January 21, 2020 - 6 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email