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News and Trends 3 Feb 2023

UK approval for AbbVie Crohn’s disease drug

AbbVie has announced that the UK Medicines and Healthcare products Regulatory Agency (MHRA) has approved RINVOQ (upadacitinib), a janus kinase (JAK) inhibitor, for the treatment of adult patients with moderately to severely active Crohn’s disease (CD) who have had an inadequate response, lost response or were intolerant to either conventional therapy or a biological agent. […]

February 3, 2023 - 3 minutesmins - By Jim Cornall

Opinion 3 Feb 2023

AI and experiments: new possibilities emerge in 2023

By Markus Gershater, co-founder and chief scientific officer, Synthace The buzz surrounding generative AI has reached fever pitch. It’s a technology so unique and fascinating that the breadth of possibility has done that rare thing of exciting both consumer and business imaginations at the same time. It’s not hard to see why. In the life […]

February 3, 2023 - 5 minutesmins - By External Contributor

News and Trends 3 Feb 2023

AI boosts genome editing

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options. Unintentional errors in the correction of DNA mutations of genetic diseases can thus be reduced. Genome editing technologies offer great opportunities for treating genetic diseases. Methods such as the widely used […]

February 3, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 3 Feb 2023

Genoscience Pharma receives orphan drug designation for hepatocellular carcinoma drug

Genoscience Pharma has announced that its lead candidate, ezurpimtrostat, a PPT-1 (Palmitoyl Protein Thioesterase-1) inhibitor, has been granted orphan drug designation (ODD) by the US Food and Drug Administration (FDA) for the treatment of hepatocellular carcinoma (HCC). ODD qualifies ezurpimtrostat for a potential seven years of market exclusivity after approval. The FDA’s ODD program provides […]

February 3, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 3 Feb 2023

Via Scientific launches with multi-omics analytics platform

Via Scientific, Inc., a new U.S.-based technology and AI company, has launched Foundry, a multi-omics accelerator platform focused on significantly shortening the path to scientific breakthroughs. The Foundry platform was originally developed at UMass Chan Medical School. Via Scientific has exclusive commercial rights to the platform. Founders of the company are Melissa J. Moore, chief […]

February 3, 2023 - 3 minutesmins - By Jim Cornall

Opinion 2 Feb 2023

How digital biomarker assays can harness the power of deep learning from clinical trials to the clinic

By Joe Oakley, MD, medical director of biomarker development, Paige Just as much of medicine has begun to undergo a digital transformation in the past decade, so has pathology. Now, biomarkers, which are indications of particular features of cancer and are essential to diagnosis and treatment, are beginning their own digital revolution. This is an […]

February 2, 2023 - 8 minutesmins - By External Contributor

News and Trends 2 Feb 2023

Crown Bioscience acquiring Indivumed’s service business and biobank

Crown Bioscience, a global contract research organization (CRO) and a JSR Life Sciences company, has entered into an agreement to acquire the IndivuServ business unit of Indivumed GmbH. A share purchase agreement (SPA) between was executed in December, 2022, and subject to customary closing adjustments, the transaction is expected to close in April 2023. Indivumed […]

February 2, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 2 Feb 2023

Orbit Discovery and Endevica Bio to develop cachexia therapeutics

Orbit Discovery Limited has entered into a multi target research agreement with Endevica Bio Inc. Endevica creates first-in-class therapeutics for cachexia caused by cancer and other chronic conditions. Its lead compound has proven to be safe and well-tolerated in phase 1 trials. The collaboration aims to accelerate Endevica’s development of advanced G-protein coupled receptor (GPCR)-targeting […]

February 2, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 2 Feb 2023

Almost 20% of cancer trials have recruited only one patient

Phesi Inc., a global provider of clinical development data analytics, has published an analysis of site-level enrolment data from 173 cancer clinical trials conducted in the past three years. The data, spanning 83,916 cancer patients from 57 countries, reveals that of the 11,826 investigator sites participating in these trials, 2,298 (19%) enrolled just one patient […]

February 2, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 2 Feb 2023

Recurv Pharma receives funding for cancer therapy development

Recurv Pharma Inc. is receiving up to $24 million in funding from TVM Capital Life Science through its TVM Life Science Innovation II SCSp fund. Recurv Pharma plans to develop a novel taxane therapy to treat solid tumors to the proof-of-concept stage. The U.S. based biotech firm is the eighth early-stage or project-focused company (PFC) […]

February 2, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 2 Feb 2023

Possible drug targets from Korean atherosclerosis research

Research suggests that the enzyme phosphoenolpyruvate carboxykinase 2 (PCK2) and its gene play a role in the development of vascular injury and atherosclerosis. Atherosclerosis is a deadly disease; research suggests that proliferation of vascular smooth muscle cells (VSMCs) and formation of a neointimal layer along the inner lining of arteries play a major role in […]

February 2, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 2 Feb 2023

AstraZeneca creates FRAGLER for DNA synthesis

“Plasmids are critical for so many processes in early drug discovery,” says David Öling, associate principal scientist at AstraZeneca. “From protein production, cell line engineering, CAR-T cell therapy, viral vector generation, therapeutic genome editing, mRNA/vaccine production and more. The time it takes and the cost of producing plasmids for DNA constructs is a critical limiting […]

February 2, 2023 - 6 minutesmins - By Jim Cornall

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Illuminating biotech in the City of Light: Inside Paris’s thriving ecosystem

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UK approval for AbbVie Crohn’s disease drug

AI and experiments: new possibilities emerge in 2023

AI boosts genome editing

Genoscience Pharma receives orphan drug designation for hepatocellular carcinoma drug

Via Scientific launches with multi-omics analytics platform

How digital biomarker assays can harness the power of deep learning from clinical trials to the clinic

Crown Bioscience acquiring Indivumed’s service business and biobank

Orbit Discovery and Endevica Bio to develop cachexia therapeutics

Almost 20% of cancer trials have recruited only one patient

Recurv Pharma receives funding for cancer therapy development

Possible drug targets from Korean atherosclerosis research

AstraZeneca creates FRAGLER for DNA synthesis

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Illuminating biotech in the City of Light: Inside Paris’s thriving ecosystem

ASCO 2025: key highlights in cancer therapeutics

New report: Artificial intelligence and the future of antibody discovery

Stem cell therapy: a potential cure for hearing loss?

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

Illuminating biotech in the City of Light: Inside Paris’s thriving ecosystem

ASCO 2025: key highlights in cancer therapeutics

New report: Artificial intelligence and the future of antibody discovery

Stem cell therapy: a potential cure for hearing loss?

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

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