News and Trends 17 Aug 2022 AUM LifeTech secures $400,000 grant for lung cancer immunotherapy program …in the most challenging circumstances, especially during the COVID-19 period,” Hancock said. “We have, slowly but steadily, generated very encouraging data showing the potency of our approach, including in humanized… August 17, 2022 - 3 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
In Depth 27 Jun 2024 CRISPR-Cas13: how does the technology compare to its famous Cas9 cousin? …mini-dCas13X–mediated RNA editing restored dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy. Targeting RNA with CRISPR-Cas13: a promising future? As revolutionary as CRISPR-Cas9 gene-editing tools have been,… June 27, 2024 - 7 minutesmins - By Willow Shah-Neville Share WhatsApp Twitter Linkedin Email
News and Trends 23 Nov 2022 First patients dosed with Infex Therapeutics’ RESP-X for chronic respiratory disease …humanized monoclonal antibody designed to help the body tackle Pa infections, a hard-to-treat, drug-resistant pathogen recognized by the WHO as a critical threat to human health. It does not kill… November 23, 2022 - 3 minutesmins - By Liza Laws Share WhatsApp Twitter Linkedin Email
News and Trends 12 Jan 2024 AI and a brain organoid: can this combo take on supercomputers? …because mouse models that are advanced and contain humanized sequences have fallen short of capturing Alzheimer’s disease pathology. These organoids are capable of simulating the environment in an Alzheimer’s brain,… January 12, 2024 - 5 minutesmins - By Roohi Mariam Peter Share WhatsApp Twitter Linkedin Email
News and Trends 23 Nov 2022 Trial to start for new heart attack drug …immediate care provided for a heart attack is effective for improving patient survival, there is more we can do to prevent long-term damage to the heart.” Glenzocimab, a humanized monoclonal… November 23, 2022 - 3 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
News and Trends 1 Aug 2022 Zenas BioPharma gets Chinese approval for thyroid eye disease treatment study …treatment options are limited and often involve high doses of steroids associated with serious side effects or surgical intervention. ZB001 is a differentiated humanized monoclonal antibody targeting insulin-like growth factor… August 1, 2022 - 3 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
News and Trends 14 Mar 2017 Can Roche & MorphoSys beat the odds in new Alzheimer’s Phase III Trials? …its approach is still very similar to that of Eli Lilly. The main differences between both candidates are that gantenerumab is fully human, instead of a humanized mouse antibody, and… March 14, 2017 - 2 minutesmins - By Clara Rodríguez Fernández Share WhatsApp Twitter Linkedin Email
Best in Biotech 19 Dec 2023 Nine biotech companies to watch in 2024 …noteworthy entry into the clinical-stage biopharmaceutical sector. At the heart of Aiolos Bio’s mission is AIO-001, a humanized anti-TSLP monoclonal antibody, developed as a treatment for moderate-to-severe asthma. This antibody… December 19, 2023 - 12 minutesmins - By Jules Adam Share WhatsApp Twitter Linkedin Email
News and Trends 7 Jul 2023 FDA approves Alzheimer’s treatment …to eligible patients as soon as possible.” LEQEMBI is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid beta (Aβ). Critically,… July 7, 2023 - 5 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
News and Trends 20 Oct 2022 Tiziana Life Sciences looks to phase 1 trial for intranasal Alzheimer’s drug …NI-0401), the only entirely human anti-CD3 mAb, has shown reduced release of cytokines after IV administration in healthy volunteers and in patients with Crohn’s disease. In a humanized mouse model… October 20, 2022 - 3 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
News and Trends 18 Nov 2016 14 More Stories: CRISPR enters Humans, Biocartis makes a Splash …to Avidea. Tiziana Life Sciences is developing fully human antibodies as an oral therapy for NASH and autoimmune diseases, and it seems to be going well in humanized mouse models…. November 18, 2016 - 2 minutesmins - By Evelyn Warner Share WhatsApp Twitter Linkedin Email
Startup Scout 23 Jun 2017 This Newly Founded French Biotech is All About Vaccines …accelerate the clinical development of its lead assets. A serious competitor could be UK-based Kymab, which is also developing a number of vaccine candidates based on its humanized Kymouse. Images… June 23, 2017 - 1 minutemin - By Melanie De Almeida Share WhatsApp Twitter Linkedin Email