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CRISPR

In Depth 15 Jan 2025

CRISPR: The gene editing tool changing the world (2025 update)

…the DNA sequence stored within CRISPR patterns and cut any DNA molecules with a matching sequence. But it wasn’t until 2012 that Jennifer Doudna and Emmanuelle Charpentier took the discovery…

January 15, 2025 - 9 minutesmins - By Jules Adam

paris biotech companies

Best in Biotech 4 Nov 2022

Get to know 15 of the best biotech companies in Paris

…as the applicability of the skin patch technology for vaccines. DNA Script DNA Script is developing a new method of synthesizing DNA — called enzymatic DNA synthesis — that has…

November 4, 2022 - 11 minutesmins - By Omnia Ibrahim

Bridge RNA

In Depth 8 Jul 2024

Bridge RNA: A new gene editing technique that could overcome the limitations of CRISPR

…pastes DNA] in a single-step mechanism that recombines and re-ligates the DNA, leaving it fully intact. This is very distinct from CRISPR editing, which creates exposed DNA breaks that require…

July 8, 2024 - 5 minutesmins - By Willow Shah-Neville

epigenetics liquid biopsy base genomics

News and Trends 8 Jun 2020

UK Startup Launches with €10M to Detect Epigenetic Signs of Cancer in Blood

…“For example, DNA methylation is retained when storing DNA for a long time, and DNA methylation is retained in fragmented DNA such as the cell-free DNA, the DNA type that…

June 8, 2020 - 3 minutesmins - By David Kirk

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CDMO Gene Cell Therapy

Interview 23 Nov 2020

CDMOs Are the Unsung Heroes of the Gene and Cell Therapy Revolution

…form of synthetic DNA, called doggyboneDNA, that is designed to simplify the manufacturing of DNA vaccines and gene therapy. To meet the ever-increasing demand for its products, Touchlight Genetics created…

November 23, 2020 - 5 minutesmins - By Helen Albert

Next generation sequencing Nick McCooke Solexa DNA electronics

Interview 11 Mar 2019

The Man Behind Next-Generation Sequencing

…Illumina unless you’ve got something which is a lot better or you’re doing something very, very different. Tell me more about this new technology being developed at DNA Electronics. DNA…

March 11, 2019 - 9 minutesmins - By Clara Rodríguez Fernández

cell chromatin

News and Trends 21 Apr 2023

New discovery “an area of cancer research with tremendous promise for breakthroughs”

…the two daughter cells. This mechanical breakage induces massive fragmentation of DNA, resulting in the formation of micronuclei and DNA released into the cytosolic DNA, which can trigger immune responses…

April 21, 2023 - 4 minutesmins - By Jim Cornall

Unlocking AAV gene therapy potential: The role of successful characterization

Sponsored by 5 Nov 2024

Unlocking AAV gene therapy potential: The role of successful characterization

…amount of DNA packaged into individual capsids can vary, resulting in AAV subpopulations with no DNA, less DNA, or even more DNA than intended. Research has shown that the innate…

November 5, 2024 - 8 minutesmins - By Ute Boronowsky

Epigenetics companies

Best in Biotech 2 Aug 2024

Six epigenetics companies making strides in 2024

…mechanisms include DNA methylation and histone modifications. DNA methylation is the attachment of chemical compounds called methyl groups to DNA so as to activate or silence a gene, whereas histone…

August 2, 2024 - 7 minutesmins - By Roohi Mariam Peter

Brink Tx recombinases

News and Trends 16 Apr 2025

Beyond CRISPR: Brink Therapeutics raises $4 million with engineered recombinases

…insertion of a therapeutic transgene into a DNA site of interest, we have to rely on additional machinery such as a host cell’s endogenous DNA repair pathways to complete the…

April 16, 2025 - 7 minutesmins - By Jules Adam

bitcoin 2.0 cover

In Depth 23 Jun 2021

How Blockchain Companies Are Helping Us Protect Our Genomic Data

…called the DNAtix token. “Each person owns his or her own DNA. If it’s DNA connected to their wallet and it’s encrypted, only they have access to their DNA. So…

June 23, 2021 - 7 minutesmins - By Helen Albert

mRNA vaccine DNA

News and Trends 5 May 2023

Exothera partners with Quantoom and launches DNA business unit

Exothera has partnered with Quantoom Biosciences to gain access to Quantoom’s Nfinity technology, a continuous production platform for RNA. The partnership will enable Exothera to be the first CDMO in…

May 5, 2023 - 2 minutesmins - By Jim Cornall