In Depth 6 Jun 2024
CRISPR: A promising path to treating blindness
…to cut DNA at the site of the mutation. “The guide RNA serves as a GPS for the cleaving enzyme to target the mutated DNA. After the mutated DNA is…
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News and Trends 10 Mar 2025
23andMe: the collapse of a genomics giant
…affordable to the American public led to a boost in sales. People flocked to get their DNA tested, and by 2015, 23andMe had genotyped one million DNA samples. It snagged…
Best in Biotech 3 Dec 2024
Twelve gift ideas for a biotech enthusiast this holiday season
…up of your own DNA – yes, that sounds pretty niche – and you have some money to spare this December, DNA11 sells DNA portrait kits that come in different…
News and Trends 27 Jan 2023
Onxeo to study prostate cancer drug
…AsiDNA Onxeo’s AsiDNA is a highly differentiated, clinical-stage first-in-class candidate in the field of DNA damage response (DDR) applied to oncology. Its decoy and agonist mechanism acting upstream of multiple…
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News and Trends 14 Dec 2016
Liquid Biopsies: Lowering the Defenses of Resistant Lung Cancer
…the extraction of cancer cell DNA. However, cfDNA is fragmented and present only in tiny amounts; and DNA from other cells is also circulating, which make the DNA belonging to…
In Depth 25 Sep 2023
Base editing hits the clinic in the U.S.
…of DNA is cut. Whereas, in contrast, CRISPR, relies on the Cas 9 enzyme to cut both strands of the DNA at the site, which can lead to accidental insertions…
News and Trends 6 Jun 2025
Beyond CRISPR: What CAST could bring to genome editing
…the risks of double-strand breaks. Base editing enables single-letter DNA changes, while prime editing allows for broader modifications, including insertions and deletions, all without cutting both strands of DNA. These…
News and Trends 3 Feb 2023
AI boosts genome editing
…information, which is then transcribed by a “translation enzyme” and incorporated into the DNA. Finding the most efficient DNA repair options Prime editing promises to be an effective method of…
In Depth 10 Mar 2023
Can CRISPR bring back extinct animals?
…on splicing bits of this DNA into the genome of its closest relative, the Asian elephant, which shares 99.6% of its DNA. Colossal also announced in January 2023 that it…
Best in Biotech 14 Jul 2025
Top biotech books of all time
…A. Doudna, Samuel H. Sternberg Pioneer in CRISPR gene editing Jennifer Doudna and biochemist Samuel H. Sternberg narrate the story behind the discovery of CRISPR, a game-changing technology that could…
In Depth 4 Apr 2024
Seven diseases CRISPR technology could cure
…of repetitive patterns found in the DNA of bacteria that form the basis of a primitive immune system, defending them from viral invaders by cutting their DNA. Using this natural…
News and Trends 24 Apr 2020
Big €10M Seed Round Funds New Class of Cancer Drugs in Switzerland
…block a DNA repair process called break-induced replication, which was discovered by the company’s scientific founder Thanos Halazonetis. This process is used by cancer cells to prevent DNA damage caused…
