CRISPR Archives

News and Trends 9 Dec 2022

Actinium Pharmaceuticals and Columbia University to study Actimab-A in AML patients

Actinium Pharmaceuticals, Inc. has entered into a research collaboration with Columbia University to study Actimab-A, its clinical-stage CD33 targeting radiotherapeutic, with engineered hematopoietic stem cells (eHSCs) modified by CRISPR/Cas9 gene editing technology to knock out CD33 expression. Siddhartha Mukherjee, assistant professor of Medicine at Columbia University Medical Center in the Department of Medicine and Division […]

December 9, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 25 Nov 2022

New function of CRISPR gene scissors discovered

For several years, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine. Researchers from the Institute of Structural Biology at the University Hospital Bonn (UKB) in Germany and the Medical Faculty of the University of Bonn, in cooperation with the partner University of St Andrews in Scotland and the European Molecular […]

November 25, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 21 Nov 2022

FMRP – the protein behind immunotherapy resistance

Immunotherapy is a cutting-edge approach to treating cancer by turning the patient’s own immune system against their tumor. Despite success rates, immunotherapy has time and again met with a stubborn obstacle: tumor cells often evade the “radar” of immune cells seeking to destroy them. This in turn leads to treatment resistance, which in many cases […]

November 21, 2022 - 6 minutesmins - By Jim Cornall

CRISPR, CRISPR-Cas9, genome-editing, gene therapy

News and Trends 11 Nov 2022

PACT Pharma reports data from CRISPR cancer study

PACT Pharma, Inc. has reported data from the first clinical study using CRISPR gene editing technology to substitute a gene in patients’ immune cells to treat cancer. Results from the study, which was conducted with collaborators at nine academic centers using PACT Pharma’s platforms, demonstrated early proof-of-concept that a patient’s immune system can be reprogrammed […]

November 11, 2022 - 5 minutesmins - By Jim Cornall

News and Trends 4 Nov 2022

Companies with exclusive rights to CRISPR diagnostic methods sign agreement

Two companies with sole rights to two CRISPR diagnostic methods in markets outside the U.S. and Greater China have signed a licensing agreement. Sherlock Biosciences announced today (November 3) that it has signed a deal with China-based Tolo Biotech which grants co-exclusive rights to the Cas12 and Cas13 method patents. As the only two companies […]

November 4, 2022 - 3 minutesmins - By Liza Laws

News and Trends 20 Oct 2022

The role of long-read sequencing in validating CRISPR outcomes

Neil Ward, general manager of PacBio EMEA With applications of CRISPR across the spectrum of microbial, plant and gene therapy increasingly being realised, enthusiasm from the research community for this technology is not expected to wane. It has the potential to, among other applications, create knock-out animal models for use in research, revolutionise agriculture and […]

October 20, 2022 - 3 minutesmins - By External Contributor

Caszyme crispr climate change Anastasiia Slynko

Interview 17 Oct 2022

CRISPR gene editing: a key tool for counteracting climate change

Monika Paulė, CEO and co-founder of the Lithuanian CRISPR developer Caszyme, explains how gene editing technology could fight climate change by boosting agriculture and biodiversity. The invention of CRISPR-Cas gene editing technology in the last decade sparked a revolution in biology, providing researchers a way to make selective and precise changes to an organism’s genetic […]

October 17, 2022 - 6 minutesmins - By Jonathan Smith

News and Trends 17 Oct 2022

Way to transform Cas-9 protein into spherical nuclear acid developed

A team of researchers at U.S. Northwestern University has developed a way to transform the Cas-9 protein into a spherical nuclear acid (SNA). It can then be loaded with critical components as required to access a broad range of tissue and cell types, as well as the intracellular compartments required for gene editing. The team […]

October 17, 2022 - 4 minutesmins - By Liza Laws

News and Trends 17 Oct 2022

Italian study shows CRISPR/Cas9 deletion of Interleukin-30 reduces prostate cancer growth

Metastatic prostate cancer is a leading cause of cancer death in men worldwide. Interleukin (IL)-30, a cytokine that may perform immunomodulatory functions, promotes prostate cancer onset and development, but whether it can be a suitable therapeutic target remains to be investigated. In a new study published in the Journal of Hematology & Oncology, researchers at […]

October 17, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 17 Oct 2022

PerkinElmer’s Horizon Discovery: the lowdown on base editing

PerkinElmer’s Horizon Discovery provides cell engineering tools and services for researchers in drug discovery and development. Horizon’s portfolio is focused on research reagents; screening and cell line engineering services; bioproduction cell lines; reference standards and base editing. Horizon’s base editing platform, Pin-point is a gene editing method with the ability to effect multiple single base edits […]

October 17, 2022 - 5 minutesmins - By Jim Cornall

News and Trends 17 Oct 2022

The challenges of translating CRISPR to the clinic

CRISPR-Cas9 is revolutionizing all facets of drug discovery, allowing for both a deeper understanding of disease processes, and for the development of ground-breaking genetic medicines. As these new classes of cell and gene therapies translate to the clinical setting, some key bottlenecks remain to be solved before the technology will realize its full societal impact. […]

October 17, 2022 - 6 minutesmins - By Jim Cornall

CRISPR Therapeutics, CRISPR-Cas9, genome editing, biotech

News and Trends 17 Oct 2022

CRISPR/Cas9: Challenges and outlook from an investor’s perspective

A Q&A with Fady Riad, CEO of consulting company Centurion Life Sciences. How did CRISPR/Cas9 revolutionize gene editing and the broader life sciences industry? CRISPR/Cas9 is undoubtedly one of the greatest scientific advancements of the last 100 years. In 2012, Jennifer Doudna and Emanuelle Charpentier published a peer-reviewed paper discussing the use of CRISPR/Cas9 in […]

October 17, 2022 - 6 minutesmins - By External Contributor

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CRISPR

Actinium Pharmaceuticals and Columbia University to study Actimab-A in AML patients

New function of CRISPR gene scissors discovered

FMRP – the protein behind immunotherapy resistance

PACT Pharma reports data from CRISPR cancer study

Companies with exclusive rights to CRISPR diagnostic methods sign agreement

The role of long-read sequencing in validating CRISPR outcomes

CRISPR gene editing: a key tool for counteracting climate change

Way to transform Cas-9 protein into spherical nuclear acid developed

Italian study shows CRISPR/Cas9 deletion of Interleukin-30 reduces prostate cancer growth

PerkinElmer’s Horizon Discovery: the lowdown on base editing

The challenges of translating CRISPR to the clinic

CRISPR/Cas9: Challenges and outlook from an investor’s perspective

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