In Depth 12 Feb 2024
RNA editing set to take off: could DNA’s short-lived cousin overcome the limitations of CRISPR gene editing?
Find out all about about RNA editing, as two candidates have just managed to reach the clinic for the first time.
Gene editing
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Best in Biotech 22 Jan 2024
Eight newly approved drugs that could become blockbusters in 2024
The much-awaited Drugs to Watch list by Clarivate is out. Let’s do a deep dive into the therapies that made the cut in 2024.
Podcast 19 Jan 2024
Epigenetic editing – the power of CRISPR without cutting DNA
Epic Bio is an epigenetic editing company, leveraging the power of CRISPR without cutting DNA. The company’s proprietary Gene Expression Modulation System (GEMS) includes the smallest Cas protein known to work in human cells. This enables in vivo or ex vivo delivery via a single viral vector. Epic’s lead program, EPI-321, is in IND-enabling studies […]
Podcast 5 Jan 2024
Gene editing in the microbiome could provide acne solution
Explore Eligo Bioscience’s groundbreaking CRISPR-based approach, modifying the microbiome to combat moderate to severe acne.
Best in Biotech 20 Dec 2023
Wrapping up 2023: A recap of top biotech moments of this year
2023 has been an exciting year for the industry. Here are some of the most notable biotech developments in 2023.
News and Trends 6 Dec 2023
A gene editing milestone: The FDA approves CASGEVY, the first CRISPR-based therapy
Still a relatively new technology, CRISPR has been heralded in recent years as having the potential to tackle a range of diseases. And now, it has finally proved its worth. In a world first, the U.S. Food and Drug Administration (FDA) has approved CASGEVY – the CRISPR-based gene therapy developed by Vertex Pharmaceuticals and CRISPR […]
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In Depth 5 Oct 2023
Saving lives with xenotransplantation: how biotechs are solving the transplant shortage crisis
On January 7, 2022, a surgery was performed on David Bennett to give him a new heart. But this was no ordinary transplant surgery. Instead of receiving a heart from a human donor, the 57-year-old, who did not qualify for a traditional transplant, received a pig heart. This surgery marked a historic breakthrough, becoming the […]
In Depth 25 Sep 2023
Base editing hits the clinic in the U.S.
Over the past couple of years, base editing, a recent offshoot of the heralded CRISPR/Cas 9 technology, has been doing its rounds in the biotech space. Now, base editing has finally set foot into clinical trials for the first time in the U.S.. American precision medicine company Beam Therapeutics treated its first patient with its […]
In Depth 19 Jul 2023
Genetic engineering giants: is China poised to lead the way?
For many people, when they hear China and genetic engineering in the same sentence, it is often synonymous with scandal, and gene-edited babies may spring to mind. And, although it is true that nearly five years ago, researcher He Jiankui infamously claimed he had created the first ever gene-edited babies, before going to prison for […]
News and Trends 28 Jun 2023
New platform cuts time engineering and selecting genome editors
A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed a new way to break through the current limited throughput in optimizing precise genome editors at scale, engineer hundreds of base editor variants in parallel instead of current one-by-one testing, and informing users of the most suitable ones […]
News and Trends 23 May 2023
HuidaGene Therapeutics creates world’s first ‘G to Y’ DNA base-editor
HuidaGene Therapeutics, a clinical-stage genome-editing company, says the National Science Review has published data from its study of the world’s first DNA base editor converting guanine to cytosine/thymine (pyrimidine), or G-to-Y. The company has filed an international patent application for the glycosylase-based guanine base editor (gGBE) and owns the exclusive global rights to the underlying […]
Best in Biotech 4 May 2023
Five advancements in lupus research over the past year
A condition that affects around five million people worldwide, lupus has no proven cure. But various treatments for the disease have been around for more than a century, and lupus research has grown over the years. The first kind of therapy for the autoimmune disease – which occurs due to an overactive immune system that […]
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