Interview 11 Sep 2018
How To Break Into The Crowded Immuno-Oncology Space
…like for the clinician and the patient trying to get access to that product. That might sound like a simple thing to say, but while clinicians in the hematological centers…
Search Results for: T cells
News and Trends 14 Nov 2018
CAR-T Promise for Patients with Solid Tumors
…is a procedure in which a patient’s immune T cells are modified to produce proteins on their surface that let them hunt cancer cells. The cells then get injected back…
In Depth 23 Nov 2023
The next frontier in immunotherapy? CAR-Macrophages as a novel cancer treatment strategy
…tumor microenvironment (TME) and prevent immune cells from effectively responding. It is an area where conventional treatments, be it checkpoint inhibitors or CAR-T cell therapies, struggle to gain traction. CAR-T…
News and Trends 10 Jan 2025
The in vivo revolution: How Interius, Umoja, and Vyriad are transforming CAR-T cell therapy
…1 trial for Interius BioTherapeutics’ in vivo CAR gene therapy INT2104 The investigational therapy INT2104 is a single dose that is delivered intravenously to patients. It is designed to target…
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Startup Scout 16 Aug 2019
This Biotech Fights Alzheimer’s Disease by Targeting Support Brain Cells
…by targeting the protein amyloid-beta. Reynolds told me that, while amyloid-beta is likely important in the early stages of Alzheimer’s disease, it could be too late to target this protein…
News and Trends 9 Feb 2017
Alma Bio Therapeutics is Aiming to Revolutionize the Treatment of IBD
…closer to a Treg vaccine that recognizes a patient’s specific repertoire of self-antigens: it distinguishes between these and the “correct” ones to act only when required. To us, our technology…
News and Trends 10 Nov 2022
SOTIO reveal potential treatment for adults with solid tumors at SITC meeting
…therapy has made significant strides in the treatment of hematological malignancies, yet solid tumors remain resistant to current CAR-T strategies due to suppression by the tumor microenvironment. “The preclinical data…
In Depth 25 Dec 2024
When biotech makes Christmas miracles a reality
…explore alternative options. They turned to trametinib, a drug initially developed to treat melanoma. This targeted therapy inhibits MEK1 and MEK2, proteins that play a crucial role in the MAPK/ERK…
Best in Biotech 2 Sep 2021
The top 15 biotech companies to find in the Netherlands
…top of chemotherapy. Lava Therapeutics Founded: 2016 Lava Therapeutics develops cancer immunotherapies that use antibodies to recruit gamma-delta T cells – a type of immune cells that are naturally involved…
News and Trends 30 Sep 2019
€20M Series A Launches Cancer Immunotherapy Biotech in Denmark
…tumor cells. This signal then tells immune cells in the tumor microenvironment to attack the tumor. STipe’s treatments are designed to make the immune cells’ STING alarm signal more sensitive…
News and Trends 19 Dec 2018
Italian Biotech Raises Big Series A for ‘Gene Therapy 2.0’
…would be the first gene therapy to target a disease that is not caused by a single gene. “This opens the path to gene therapy 2.0, where the target includes…
In Depth 30 Dec 2020
A Look Back at the Past Decade of European Biotech
…saw the US approval of Kymriah, the world’s first CAR-T cell therapy. This treatment consists of engineering the patient’s own immune cells to make them better at identifying and attacking…
