News and Trends 17 Oct 2022 The challenges of translating CRISPR to the clinic …shuffling. How is the field coping with this finding? CRISPR-Cas9 works by cutting DNA within a gene and allowing error-prone DNA repair to introduce errors in the hope that these… October 17, 2022 - 6 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
News and Trends 12 Dec 2016 With a new €120M Infusion, Pocket NGS CEO talks Success and Strategy …machines for specialized life science labs, this company is democratizing genome sequencing to make it available to nonspecialized users. As Sanghera remarked, “We think long and hard about ubiquitous DNA… December 12, 2016 - 9 minutesmins - By Evelyn Warner Share WhatsApp Twitter Linkedin Email
News and Trends 9 Aug 2022 Study says gene editing with CRISPR/Cas9 can lead to cell toxicity and genome instability …cancer and other DNA damage-related complications. CRISPR gene editing often requires cutting both DNA strands. In some cases, this manipulation can trigger a p53 response, in which edited cells can… August 9, 2022 - 3 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
News and Trends 26 Oct 2017 New and Improved CRISPR: More Precise Genome Editing Now Possible …gives us the power to rewrite errors in the genetic code instead of cutting out large chunks of DNA. Base editing targets individual DNA bases (cytosine, guanine, adenine and thymine),… October 26, 2017 - 3 minutesmins - By Alex Dale Share WhatsApp Twitter Linkedin Email
Best in Biotech 11 Jul 2024 From data to discovery: Five bioinformatics companies you should know in 2024 …variants contain restriction sites, codons are changed to avoid creating restriction sites. Twist’s DNA synthesis platform is then employed to print each variant. The DNA is then amplified to create… July 11, 2024 - 7 minutesmins - By Roohi Mariam Peter Share WhatsApp Twitter Linkedin Email
Best in Biotech 7 Jan 2019 15 European Biotech Companies to Watch in 2019 …Script is developing a new biological method of synthesizing DNA that has the potential to significantly reduce the time it takes to make custom DNA sequences in the lab. This… January 7, 2019 - 9 minutesmins - By Clara Rodríguez Fernández Share WhatsApp Twitter Linkedin Email
In Depth 27 Jun 2024 CRISPR-Cas13: how does the technology compare to its famous Cas9 cousin? …single guide RNA (sgRNA) to target and cleave DNA, whereas CRISPR-Cas13, despite also being an RNA-guided nuclease, targets RNA instead of DNA. CRISPR-Cas13 also indiscriminately cleaves single-stranded RNA (ssRNA) when… June 27, 2024 - 7 minutesmins - By Willow Shah-Neville Share WhatsApp Twitter Linkedin Email
Interview 5 Apr 2021 Base Editing: The Next Frontier in Genome Editing Technology …using a template of exogenous DNA along with the introduction of DNA double-strand breaks using nuclease-based technologies, such as CRISPR, ZFNs, or TALENs. Although these approaches can be precise, their… April 5, 2021 - 4 minutesmins - By Larissa Warneck-Silvestrin Share WhatsApp Twitter Linkedin Email
News and Trends 5 Jun 2023 Bacterial resistance genes a ‘threat to human health’ …been on identifying those resistance genes that are already prevalent in pathogenic bacteria. Instead, in the new study, researchers looked at large quantities of DNA sequences from bacteria to analyze… June 5, 2023 - 5 minutesmins - By Jim Cornall Share WhatsApp Twitter Linkedin Email
Best in Biotech 16 Apr 2025 HIV innovation: Six companies developing new treatments in 2025 …in Hong Kong Science Park, Immuno Cure BioTech develops DNA vaccines and immunotherapies for infectious diseases and cancers. Its proprietary PD-1-enhanced DNA vaccine platform aims to improve immune responses by… April 16, 2025 - 9 minutesmins - By Jules Adam Share WhatsApp Twitter Linkedin Email
Best in Biotech 4 Jun 2024 Ohio’s finest: Eight biotech companies leading the way …that can degrade biofilms and increase antibiotic activity by capturing and removing DNABII proteins. These proteins act as linchpins to the structural stability of biofilm, removing them causes it to… June 4, 2024 - 9 minutesmins - By Jules Adam Share WhatsApp Twitter Linkedin Email
In Depth 31 Jan 2018 Why Does Europe Lag Behind the US and China in the Gene Editing Race? …are a number of different gene editing tools that use nuclease enzymes as ‘molecular scissors’ to cut the DNA, including zinc finger nucleases, transcription activator-like effector nucleases (TALENs), and, of… January 31, 2018 - 6 minutesmins - By Ekaterina Perets Share WhatsApp Twitter Linkedin Email