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pHion Therapeutics CEO Helen McCarthy

Interview 23 Jan 2023

Watch: pHion Therapeutics talks about next-generation mRNA vaccines

pHion Therapeutics is a U.K.-based vaccine development company. It is developing a pipeline of therapeutic and prophylactic vaccines focussed on viral infections and oncology. The company’s proprietary RALA platform can deliver anionic molecules, such as mRNA and DNA, in a stealth-like way, evading detection, to generate a potent antigen-specific CD8+ T-cell response. The RALA peptide-based […]

January 23, 2023 - 1 minutemin - By Jim Cornall

collaboration

Opinion 18 Jan 2023

Innovation in life sciences requires collaboration and community

By Claudia Tripp and Katie Nelson, Kadans Science Partner Collaboration has underpinned some of the most impactful innovations of recent years. For example, the rapid development of the COVID vaccine was only made possible due to collaboration. Pfizer’s rapidly-established partnership with BioNTech delivered the first vaccine at lightning speed. Having established an ecosystem approach to […]

January 18, 2023 - 5 minutesmins - By External Contributor

covid covid-19

News and Trends 17 Jan 2023

Ascletis phase I COVID trial progressing

Ascletis Pharma Inc. has announced the dosing of four healthy subjects in its multiple-dose escalation phase I clinical trial of oral 3-chymotrypsin like protease (3CLpro) inhibitor ASC11 in combination with 100 mg ritonavir tablets for COVID-19. The phase I clinical trial is expected to enroll 72 healthy subjects, including 60 subjects in single-dose escalation cohorts […]

January 17, 2023 - 3 minutesmins - By Jim Cornall

clinical trials

News and Trends 12 Jan 2023

Breast cancer most studied disease area in 2022

Phesi, a global provider of patient-centric data analytics, has released the results of its global analysis of all clinical trials conducted in 2022. The report, which analyzed 80,917 trial records, reveals that breast cancer retained its position as the most-studied disease area, followed by COVID-19. Three of the top five most-studied disease areas fell within oncology, […]

January 12, 2023 - 3 minutesmins - By Jim Cornall

covid covid-19

News and Trends 9 Jan 2023

ExeVir Bio secures funding for COVID program

ExeVir Bio, a Belgian biotech company developing nanobody therapies for broad protection against infectious diseases, has secured a venture debt financing agreement of up to €25 million ($26.5 million) with the European Investment Bank (EIB). The EIB financing will help advance ExeVir Bio’s lead asset, XVR012, into clinical trials for COVID-19. ExeVir Bio’s COVID-19 development […]

January 9, 2023 - 3 minutesmins - By Jim Cornall

coronavirus betacoronaviruses

News and Trends 21 Dec 2022

Ethris and DIOSynVax to develop mRNA betacoronavirus vaccine

Ethris GmbH is to collaborate with U.K.-based DIOSynVax to jointly develop a protective mRNA vaccine candidate against a broad range of betacoronaviruses. The efforts will utilize Ethris’ mRNA modification and design technologies as well as its lipidoid nanoparticle (LNP) and stabilization platforms. The collaboration is founded on a $42 million award to DIOSynVax by the […]

December 21, 2022 - 3 minutesmins - By Jim Cornall

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Leipzig Messe Germany

News and Trends 19 Dec 2022

Watch: Atriva Therapeutics at BIO-Europe

Atriva Therapeutics’ mission is to develop an antiviral therapy platform against severe respiratory and systemic diseases with a high unmet medical need induced by RNA viruses, e.g., influenza and COVID-19. The clinical-stage biopharmaceutical company is pioneering the development of host-targeting antiviral therapies, making development of viral resistance unlikely, and thereby significantly contributing to pandemic preparedness. […]

December 19, 2022 - 1 minutemin - By Jim Cornall

plasmid DNA

News and Trends 19 Dec 2022

Nykode Therapeutics and Richter-Helm BioLogics announce partnership

Nykode Therapeutics ASA has entered into a strategic manufacturing partnership with Richter-Helm BioLogics GmbH & Co KG to supply plasmid DNA for Nykode’s wholly owned and partnered product portfolio. “We are excited about the strategic manufacturing partnership with Richter-Helm BioLogics. As a leading manufacturer of DNA vaccines, they will provide the long-term expertise and capacity […]

December 19, 2022 - 3 minutesmins - By Jim Cornall

healthcare technology

News and Trends 14 Dec 2022

Tachmed aiming to make healthcare more accessible

Tachmed is looking to transform access to healthcare through technology. The company’s CEO, Paul Christie, tells us how. What is the driving force behind Tachmed? What motivated you to work towards transforming digital diagnostics technology? It was during my private equity career that the idea of Tachmed was born. I was with a team running […]

December 14, 2022 - 4 minutesmins - By Jim Cornall

covid covid-19

News and Trends 14 Dec 2022

Startup USSF bringing oral COVID vaccine to market

From a small biotech start-up firm in Allentown, Pennsylvania, two scientists are leading their team to bring an oral COVID-19 vaccine to market – one that will be easier to use, longer lasting and with fewer side effects. Kyle Flanigan and Garry Morefield co-founded US Specialty Formulations LLC (USSF) through discussions while watching their daughters […]

December 14, 2022 - 5 minutesmins - By Jim Cornall

covid

News and Trends 13 Dec 2022

Ascletis announces positive COVID-19 trial results

Ascletis Pharma Inc. has announced positive topline results from its phase I multiple ascending dose (MAD) study in healthy subjects for oral RNA-dependent RNA polymerase (RdRp) inhibitor ASC10 for COVID-19 treatment. Ascletis’ ASC10 is an innovative orally available double prodrug, which has a new and differentiated chemical structure from the single prodrug molnupiravir. After oral […]

December 13, 2022 - 3 minutesmins - By Jim Cornall

covid covid-19

News and Trends 8 Dec 2022

MetrioPharm reveals COVID-19 study data

MetrioPharm AG, a Swiss pharmaceutical company developing drugs for inflammatory diseases, has announced topline data from its CT05 phase IIa study of small molecule macrophage metabolic modulator MP1032 in COVID-19 patients. In the trial, patients received either MP1032 plus standard of care (SoC), or placebo plus SoC. SoC partially included other antivirals (Remdesivir or Nirmatrelvir/Ritonavir), […]

December 8, 2022 - 4 minutesmins - By Jim Cornall

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