Clinical trial Archives

Horizone Therapeutics, Eye disease, eye, eyes

News and Trends 9 Sep 2022

Improved vision with less eye injections for patients after primary endpoints met in trials

The primary endpoints in two clinical trials investigating drug aflibercept 8 mg with 12 and 16-week dosing regimes, for patients with diabetic macular edema (DME) and wet age-related macular degeneration (wAMD), have been met. The trials, called PHOTON in DME and PULSAR in wAMD, both showed the dosing regimens achieved non-inferiority in vision gains compared […]

September 9, 2022 - 3 minutesmins - By Liza Laws

News and Trends 8 Sep 2022

First patient dosed in China trial with drug to treat non-Hodgkin lymphoma

The dosing of the first patient at a clinical trial in China for patients with relapsed/refractory non-Hodgkin lymphoma (NHL) was announced yesterday (September 7). CASI Pharmaceuticals and BioInvent International AB are running the phase 1, dose-escalation and expansion study of BI-1206. The treatment is a fully human monoclonal antibody (mAb) that targets FcyRIIB, in combination […]

September 8, 2022 - 2 minutesmins - By Liza Laws

News and Trends 8 Sep 2022

Lutris Pharma radiation trial brings positive results for breast cancer patients

Top line results from a clinical trial treating breast cancer patients with radiation dermatitis (RD) have been positive. Lutris Pharma, based in Israel, is a biopharma company focused on improving cancer therapies. It announced its results from the open label part 1 and double blinded part 2 of it phase 1/2 trial yesterday (September 7). […]

September 8, 2022 - 4 minutesmins - By Liza Laws

News and Trends 8 Sep 2022

Report looks at the future of clinical trials

Medidata, a Dassault Systèmes company, has published a report, ‘European Industry Research Report: The Future of Clinical Trials’. The report draws on new independent research that includes insights from 400 clinical trial executives across the U.K., France, Germany and Switzerland. They were surveyed to gain a deeper understanding of how clinical trials have changed over […]

September 8, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 7 Sep 2022

Adocia takes steps with implants for treatment of type 1 diabetes

French biopharma company Adocia has established a first proof of concept for its AdoShell Islets implant by achieving glycemic control without insulin injections in immunocompetent diabetic rats during a 132-day study. AdoShell Islets is an immuno-protective synthetic biomaterial containing islets of Langerhans. After implantation in diabetic animals, the islets encapsulated in AdoShell secrete insulin in […]

September 7, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 7 Sep 2022

OncoResponse and Regeneron to evaluate drug combo for patients with advanced cancer

OncoResponse, a clinical-stage biotech company advancing immunotherapies derived from the immune systems of elite cancer responders, has announced a clinical supply agreement with Regeneron for PD-1 inhibitor Libtayo (cemiplimab). The supply agreement with Regeneron will support the evaluation of Libtayo in combination with OR2805, a fully human monoclonal antibody identified from an elite cancer responder […]

September 7, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 7 Sep 2022

Alzinova announces new positive safety review for Alzheimer’s study

Alzinova AB says a second external safety review has been carried out of its clinical phase 1b study. This resulted in a positive assessment to continue the study as planned. Behind the review is an independent expert group, Data and Safety Monitoring Board (DSMB), which continuously reviews the study. Based on the patients included in […]

September 7, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 7 Sep 2022

Ionis presents positive study results at International Symposium on amyloidosis

Ionis Pharmaceuticals, Inc. has presented positive results from a planned 35-week interim analysis of the phase 3 NEURO-TTRansform study of Ionis and AstraZeneca’s eplontersen in patients with hereditary transthyretin-mediated amyloid polyneuropathy (ATTRv-PN). In the study, eplontersen demonstrated a statistically significant and clinically meaningful change from baseline for its co-primary and secondary efficacy endpoints compared to […]

September 7, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 6 Sep 2022

IRLAB’s partner Ipsen starts mesdopetam clinical studies

IRLAB Therapeutics AB, a clinical-stage biopharmaceutical company discovering and developing novel treatments for the most troublesome symptoms of Parkinson’s disease, says its partner, Ipsen, has initiated clinical studies with drug candidate mesdopetam in accordance with its development plan. These are standard clinical pharmacokinetic studies that will run in parallel to the phase IIb study with […]

September 6, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 6 Sep 2022

Innovent starts trial of mazdutide in Chinese adults with obesity

Innovent Biologics, Inc. says the first participant has been successfully dosed in the higher-dose cohort of a phase 2 clinical trial of mazdutide, a glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR) dual agonist, in Chinese adults with obesity. This randomized, double-blinded, placebo-controlled study was designed to evaluate the efficacy and safety of mazdutide […]

September 6, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 5 Sep 2022

First patient with peripheral T cell lymphoma dosed with Yingli Pharma’s linperlisib

The first patient has been dosed in a phase 2 trial looking at a drug to treat peripheral T cell lymphomas – a heterogenous group of generally aggressive neoplasms. Yingli Pharma made the announcement on Saturday (September 3) that patients were being dosed with linperlisib – a potent inhibitor of the delta isoform of PI3 […]

September 5, 2022 - 2 minutesmins - By Liza Laws

News and Trends 5 Sep 2022

Sanofi and Regeneron’s Dupixent shows sustained improvement in lung function in children

A maintenance therapy from Sanofi and Regeneron, added to other asthma medications, has shown sustained improvement in lung function, low-rate of asthma attacks and a consistent safety profile for up to two years in children. Results from the longest global phase 3 open-label extension trial in the age group six to 11 years old with […]

September 5, 2022 - 3 minutesmins - By Liza Laws

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Clinical trial

Improved vision with less eye injections for patients after primary endpoints met in trials

First patient dosed in China trial with drug to treat non-Hodgkin lymphoma

Lutris Pharma radiation trial brings positive results for breast cancer patients

Report looks at the future of clinical trials

Adocia takes steps with implants for treatment of type 1 diabetes

OncoResponse and Regeneron to evaluate drug combo for patients with advanced cancer

Alzinova announces new positive safety review for Alzheimer’s study

Ionis presents positive study results at International Symposium on amyloidosis

IRLAB’s partner Ipsen starts mesdopetam clinical studies

Innovent starts trial of mazdutide in Chinese adults with obesity

First patient with peripheral T cell lymphoma dosed with Yingli Pharma’s linperlisib

Sanofi and Regeneron’s Dupixent shows sustained improvement in lung function in children

Subscribe to our newsletter to get the latest biotech news!

The top biotech deals of March 2025

The biggest biotech funding rounds in March 2025

Join the webinar: AI in antibody discovery - from in silico analysis to AI-enabled data management

Beyond amyloid: The search for the next big thing in Alzheimer’s treatment

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

The top biotech deals of March 2025

The biggest biotech funding rounds in March 2025

Join the webinar: AI in antibody discovery - from in silico analysis to AI-enabled data management

Beyond amyloid: The search for the next big thing in Alzheimer’s treatment

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

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