Drug discovery Archives

News and Trends 9 May 2023

Recursion boosts drug discovery with Cyclica and Valence acquisitions

Recursion has signed agreements to acquire two companies in the AI-enabled drug discovery space: Cyclica, for $40 million, and Valence, for $47.5 million. Chris Gibson, co-founder and CEO of Salt Lake City headquartered Recursion, said: “Recursion has pioneered the massive, parallel generation of -omics data with machine learning in order to map and navigate biology […]

May 9, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 3 May 2023

First drug discovered through 3D bioprinted tissue disease model

Viscient Bio, Inc. has announced it has identified the world’s first drug candidate discovered primarily using 3D bioprinted tissue models of disease formed from human cells. The company said it expects to develop the drug to treat non-alcoholic steatohepatitis (NASH), a growing epidemic disease that is believed to affect more than 10% of the U.S. […]

May 3, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 11 Apr 2023

PsychoGenics launches eCube AI platform for drug discovery

PsychoGenics Inc. has launched eCube, a pharmaco-electroencephalography (pharmacoEEG) platform to support phenotypic drug discovery. The company said that unlike traditional target-based drug discovery, this technique can identify novel treatments with multiple targets. Similar to the company’s AI-enabled, behavior-based platform, SmartCube, eCube harnesses machine learning to identify central nervous system (CNS) penetrant compounds and predict their […]

April 11, 2023 - 3 minutesmins - By Jim Cornall

artificial intelligence AI drug discovery

News and Trends 9 Mar 2023

Iktos raises €15.5M to expand AI drug discovery technologies

Iktos, a company specializing in artificial intelligence (AI) for new drug discovery, has closed a €15.5 million ($16.4 million) Series A financing co-led by new investors M Ventures and Debiopharm Innovation Fund with participation from Omnes Capital. This financing will enable Iktos to further develop its AI and drug discovery capabilities and expand its existing SaaS software […]

March 9, 2023 - 2 minutesmins - By Jim Cornall

From breast to bone: Refining metastasis drug discovery with a novel organ-on-a-chip device

Understanding invasive cancer progression and metastasis formation are among the core open questions in cancer research. However, the limitations of current models lead to high failure rates in drug development. An EU-funded consortium has designed an organ-on-a-chip approach that could deliver new insights. In metastasis, circulating tumor cells spontaneously shed from the primary site to […]

February 21, 2023 - 6 minutesmins - By Ute Boronowsky

MDI Biosciences Cardiff University. Photo/Cardiff University

News and Trends 14 Feb 2023

Astex and Cardiff University Medicines Discovery Institute to collaborate on neurodegenerative diseases

Astex Pharmaceuticals (UK), a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics for oncology and diseases of the central nervous system and The Medicines Discovery Institute, Cardiff University (MDI) have entered into a multi-year, multi-million-pound drug discovery research collaboration, aimed to identify new drugs to treat neurodegenerative diseases. The collaboration […]

February 14, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 9 Feb 2023

Icosagen receives €18M loan for R&D and new facility

The Estonian biopharma company Icosagen AS has reached an €18 million financing agreement with the European Investment Bank (EIB) backed by the InvestEU program. The funds will strengthen the company’s drug discovery, development and production services. The funds are part of Icosagen’s €40 million investment into increasing its innovative contract research and development capabilities as […]

February 9, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 2 Feb 2023

Possible drug targets from Korean atherosclerosis research

Research suggests that the enzyme phosphoenolpyruvate carboxykinase 2 (PCK2) and its gene play a role in the development of vascular injury and atherosclerosis. Atherosclerosis is a deadly disease; research suggests that proliferation of vascular smooth muscle cells (VSMCs) and formation of a neointimal layer along the inner lining of arteries play a major role in […]

February 2, 2023 - 3 minutesmins - By Jim Cornall

Opinion 1 Feb 2023

Computational chemistry and cancer

by Martin Slater, Cresset Discovery Computational chemistry offers a fast and innovative approach to drug discovery and is especially powerful when used in combination with biological testing to provide a complete and reliable picture of a target system. This is perhaps no better illustrated than in Cresset Discovery’s project with University of South Australia, which […]

February 1, 2023 - 3 minutesmins - By External Contributor

cancer cell screening drug discovery microplate

Cancer cell line screening: a compass for drug discovery

Large-panel cancer cell line screening can help find the right fit between a specific cancer cell and a therapeutic molecule, leading to the development of effective treatments. How can robust quality control, real-time screening methods, and a set of unique screening panels address current screening challenges? Human cell lines have been used in drug development […]

January 24, 2023 - 5 minutesmins - By Alexander Burik

Interview 19 Jan 2023

Interview: Proscia talks about digital pathology

Labiotech recently interviewed Nathan Buchbinder, chief product officer at Proscia, about digital pathology. AI has been a hot topic in drug discovery. Can you outline how it’s being applied to pathology data? Sure, it’s always great to start with such an exciting topic! There are two broad applications of AI that I want to highlight. […]

January 19, 2023 - 8 minutesmins - By Jim Cornall

News and Trends 12 Jan 2023

Collaboration to boost pandemic preparedness, structure-based drug discovery and vaccine design

A new Memorandum of Understanding (MoU) to facilitate collaboration in the field of pandemic preparedness and to promote further cooperation between the University of Oxford and Diamond Light Source has been announced. The University of Oxford and Diamond Light Source already have many links but now intend to develop their collaborative work to address multiple […]

January 12, 2023 - 3 minutesmins - By Jim Cornall

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