Protein Archives

News and Trends 17 Feb 2023

Avilar Therapeutics financing up to $75M to boost extracellular protein degraders pipeline

Avilar Therapeutics has raised additional funding with an expanded syndicate of new investors to support advancing a pipeline of first-in-class extracellular protein degraders. The new financing takes the company’s total to $75 million. The seed round had initial funding from Avilar’s founding investor, RA Capital Management, and now includes participation by new investors Sanofi Ventures, […]

February 17, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 23 Nov 2022

Chiesi marks start of Biotech Center of Excellence for the future of medicine in Parma

An impressive crowd gathered at Chiesi Pharmaceutical Group yesterday (November 21) to mark the much-anticipated start of work at its Biotech Center of Excellence, bringing the future of medicine to Parma. Guests, which included Vice Minister of Business and Made in Italy, Valentino Valentini, joined to celebrate the start of the work on the building, […]

November 23, 2022 - 5 minutesmins - By Liza Laws

News and Trends 21 Nov 2022

FMRP – the protein behind immunotherapy resistance

Immunotherapy is a cutting-edge approach to treating cancer by turning the patient’s own immune system against their tumor. Despite success rates, immunotherapy has time and again met with a stubborn obstacle: tumor cells often evade the “radar” of immune cells seeking to destroy them. This in turn leads to treatment resistance, which in many cases […]

November 21, 2022 - 6 minutesmins - By Jim Cornall

News and Trends 14 Nov 2022

Researchers discover protein facilitates relapse of pediatric brain tumors

The malignant brain tumor type medulloblastoma can become resistant to therapy, which can cause relapse. Researchers at Uppsala University in Sweden have discovered a protein that makes tumor cells insensitive to radiation treatment. The scientists hope the results could lead to better treatments for children with the highest risk to develop relapses. Avoiding treatment Medulloblastoma […]

November 14, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 8 Nov 2022

Google and Meta AI could boost cancer research and drug discovery

Encoded in the DNA, a protein may be represented as a thread of hundreds of individual molecules called amino acids, linked together. Depending on the particular amino acids combination, a protein folds in a particular way, resulting in a functional 3D shape. The shape makes the function, and with 20 different amino acids available, the […]

November 8, 2022 - 3 minutesmins - By Jim Cornall

News and Trends 7 Nov 2022

Proteins identified by FunSel and developed by Forcefield can preserve heart function

Forcefield Therapeutics, has presented positive preclinical data on three proteins identified by it FunSel platform that have the potential to preserve heart function following a heart attack. The company that works with therapeutics to protect heart function by arresting the loss of cardiomyocytes following myocardial infarction infarction. The paper, Novel Recombinant Cardioprotective Factors Against Myocardial […]

November 7, 2022 - 3 minutesmins - By Liza Laws

News and Trends 24 Oct 2022

New method of observing cell transport could inspire drug development

Membrane proteins are key targets for many drugs. Some of them, called transporters, move certain substances in and out of the cellular environment. Yet, extracting and storing them for observation is particularly complex. A team from the University of Geneva (UNIGE) in Switzerland, in collaboration with the University of Zurich (UZH), has developed an innovative […]

October 24, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 14 Oct 2022

A-Alpha Bio and Bristol Myers Squibb to collaborate on protein degradation

A-Alpha Bio, a synthetic biology and machine learning company that measures and engineers protein-protein interactions is to collaborate with Bristol Myers Squibb to discover molecular glue targets for protein degradation. A-Alpha will identify and characterize novel pairs of E3 ubiquitin ligases and targets that Bristol Myers Squibb will utilize for potential design and development of […]

October 14, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 12 Oct 2022

Amphista Therapeutics and Domainex Ltd partner for integrated drug services

Amphista Therapeutics Ltd., has selected Domainex Ltd as one of its trusted partners to provide integrated drug discovery services to support its research programs. The partnership will also advance its portfolio of drug discovery projects targeting protein degradation (TPD). Targeted protein degradation (TPD) is an emerging therapeutic modality with the potential to deal with disease-causing […]

October 12, 2022 - 2 minutesmins - By Liza Laws

Using the power of proteomics to predict immunotherapy responses in melanoma and beyond

Next-generation proteomics has a vital role to play in the search for new biomarkers of immunotherapy response. Recent studies in melanoma presented at the European Society for Medical Oncology (ESMO) Congress highlight how these insights have the potential to transform cancer care. The recent success of immunotherapies that manipulate the patient’s immune system to recognize […]

September 27, 2022 - 6 minutesmins - By External Contributor

News and Trends 20 Sep 2022

Texture of meat alternatives vastly improved by platform creating alternative active proteins

An Israeli start-up is using technology to clean up labels in products mimicking meat using veggie protein. Meala FoodTech Ltd using a platform to create functionally active proteins designed to replace 1:1 methylcellulose and other hydrocolloids and gums widely used in meat replacements as binding and gelling agents. Meala FoodTech says its multifunctional proteins vastly […]

September 20, 2022 - 4 minutesmins - By Liza Laws

News and Trends 30 Aug 2022

Scientists unravel mystery behind neurodegenerative disease protein

Scientists have unraveled the mystery behind the mechanism behind a type of protein that leads to a progressive nervous system disease. In a study, recently published in the journal Physical Chemistry Chemical Physics, the researchers say that the RNA-binding ‘fused in sarcoma’ (FUS) protein transitions between liquid and solid phases inside cells. The scientists from […]

August 30, 2022 - 4 minutesmins - By Liza Laws

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