Inflammatory disease Archives

News and Trends 14 Nov 2022

EpiEndo gets regulatory approval for first patient study of first non-antibiotic macrolide

EpiEndo Pharmaceuticals, a clinical-stage biopharma company developing therapeutics for chronic inflammatory diseases, has received regulatory approval to begin a phase 2a clinical trial. The trial will be with lead molecule EP395 in COPD (chronic obstructive pulmonary disease) patients, an orally available macrolide or ‘Barriolide,’ with reduced antimicrobial resistance potential. It aims to address the unmet […]

November 14, 2022 - 3 minutesmins - By Liza Laws

News and Trends 10 Nov 2022

Researchers develop new nanoparticle to deliver drugs direct to macrophages

How can a drug be delivered exactly where it is needed, while limiting the risk of side effects? The use of nanoparticles to encapsulate a drug to protect it and the body until it reaches its point of action is being increasingly studied. However, this requires identifying the right nanoparticle for each drug according to […]

November 10, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 8 Nov 2022

Lipum starts chronic inflammatory disease drug study

Lipum AB (publ) says its phase 1 clinical study with the drug candidate SOL-116 has started and is progressing according to plan. A first dose group of eight healthy volunteers have received a dose, with two volunteers receiving placebo. Lipum’s drug candidate SOL-116 is a fully humanized antibody that is intended to address a major […]

November 8, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 25 Oct 2022

Delayed release tablets to treat ulcerative colitis launched in Canada

With Canada having one of the highest incidences of ulcerative colitis in the world, the recent launch of Tillotts Pharma AG’s Octasa 800 mg will be well-received. Tillotts is part of the Japanese Zeria Group, and announced Octasa (mesalazine) delayed-release tablets, as first-line treatment for moderately active ulcerative colitis (UC) in Canada. The launch, the […]

October 25, 2022 - 2 minutesmins - By Liza Laws

News and Trends 20 Oct 2022

C4XD and HitGen to collaborate on inflammation hit identification project

Drug discovery company C4X Discovery Holdings plc and HitGen Inc., which develops DNA-encoded library (DEL) technology, are to collaborate on identifying novel, small molecule hits against an inflammatory target for further C4XD development. The aim of the project is to augment C4XD’s pipeline of small molecule inflammatory disease candidates for pre-clinical development and out-licensing to […]

October 20, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 21 Sep 2022

NodThera reveals positive results for inflammasome inhibitors

Biotech company NodThera has announced positive phase 1 clinical readouts for its first and second clinical candidates, NT-0796 and NT-0249. A phase 1 study has been completed for NT-0796, confirming brain penetration with excellent pharmacokinetic (PK) and pharmacodynamic (PD) profiles and for NT-0249, dosing of the phase 1 single ascending dose cohorts has been completed, […]

September 21, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 19 Sep 2022

Cyxone receives approval for phase 2b rheumatoid arthritis study

Swedish biotech company Cyxone has received approval from the Medical Product Agency (Office for Registration of Medicinal Products, Medical devices and Biocides) and the Central Ethics Committee in Poland to start a clinical phase 2b study with its drug candidate Rabeximod, which is being developed as a treatment for rheumatoid arthritis (RA). “The approval is […]

September 19, 2022 - 2 minutesmins - By Jim Cornall

lupus autoimmune disease neutrophil citryll

News and Trends 16 Sep 2022

Domainex’ drug shows positive data for treatment of interferonopathies

Interferonapathies such as lupus, Sjögren’s syndrome, and scleroderma could be treated effectively after positive human ex-vivo data was produced. Domainex Ltd., carried out an in-house research program to identify inhibitors of protein kinases TBK1 and IKK-epsilon and DMXD-011 has been nominated as a preclinical drug candidate. The molecule is orally-bioavailable and highly selective. Disease modifying The […]

September 16, 2022 - 2 minutesmins - By Liza Laws

News and Trends 8 Sep 2022

Arcutis Biotherapeutics acquires Ducentis BioTherapeutics in deal worth up to $400M

Arcutis Biotherapeutics, Inc. has entered into an agreement to acquire Ducentis BioTherapeutics Ltd., a privately held, preclinical-stage biotechnology company focused on developing novel therapies for inflammation and autoimmune diseases. Arcutis BioTherapeutics will acquire the outstanding shares of Ducentis for an upfront cash payment of approximately $16 million and Arcutis stock valued at approximately $14 million, […]

September 8, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 2 Sep 2022

Abivax pulls in €49.2M but needs more to complete ulcerative colitis program

French biotech company Abivax has completed an oversubscribed €49.2 million ($49 million) financing round. This included U.S. and European biotech specialist investors, led by TCGX, with participation from Venrock Healthcare Capital Partners, Deep Track Capital, Sofinnova Partners, Invus, and Truffle Capital through the completion of two transactions. The first was a reserved capital increase of […]

September 2, 2022 - 4 minutesmins - By Jim Cornall

News and Trends 31 Aug 2022

Researchers try to bridge gap in link for patients with salmonella infection and clogged arteries

Researchers from Taiwan have discovered that patients with non-typhoidal salmonella (NTS) have higher aortic calcification and elevated plasma levels, which are an inflammatory biomarker. They say their findings suggest the need for early diagnosis of the condition in patients with atherosclerosis risk factors. NTS is a foodborne bacterium causing gastrointestinal infections and can cause life-threatening […]

August 31, 2022 - 4 minutesmins - By Liza Laws

News and Trends 19 Aug 2022

World’s first CAR-T for treatment of inflammatory disorders of the central nervous system approved in China

China’s National Medical Products (NMPA) has approved an investigational new drug application from IASO Bio for the new extended indication of neuromyelitis optica spectrum disorder (NMOSD). Neuromyelitis optica spectrum disorders previously known as Devic disease or neuromyelitis optica are inflammatory disorders of the central nervous system characterized by severe, immune-mediated demyelination and axonal damage predominantly targeting […]

August 19, 2022 - 2 minutesmins - By Liza Laws

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Inflammatory disease

EpiEndo gets regulatory approval for first patient study of first non-antibiotic macrolide

Researchers develop new nanoparticle to deliver drugs direct to macrophages

Lipum starts chronic inflammatory disease drug study

Delayed release tablets to treat ulcerative colitis launched in Canada

C4XD and HitGen to collaborate on inflammation hit identification project

NodThera reveals positive results for inflammasome inhibitors

Cyxone receives approval for phase 2b rheumatoid arthritis study

Domainex’ drug shows positive data for treatment of interferonopathies

Arcutis Biotherapeutics acquires Ducentis BioTherapeutics in deal worth up to $400M

Abivax pulls in €49.2M but needs more to complete ulcerative colitis program

Researchers try to bridge gap in link for patients with salmonella infection and clogged arteries

World’s first CAR-T for treatment of inflammatory disorders of the central nervous system approved in China

Subscribe to our newsletter to get the latest biotech news!

10 biotech companies to watch in 2025

Biotech in 2024: A retrospective

Grab your free report on 3D organoids and explore their future potential

Five biosimilar companies you should know about

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

10 biotech companies to watch in 2025

Biotech in 2024: A retrospective

Grab your free report on 3D organoids and explore their future potential

Five biosimilar companies you should know about

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

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