In Depth 27 Jan 2021 Single-Cell Sequencing: Paving the Way for Precision Medicine Next-generation sequencing techniques to determine an individual’s unique genetic code gave rise to personalized treatments. Single-cell sequencing is the next step towards making precision medicine more accurate. Each cell in our body is unique. Even genetically identical cells can behave differently in response to a certain treatment. With next-generation sequencing, scientists can study how the […] January 27, 2021 - 7 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
In Depth 27 Jul 2020 Biosensors: Monitoring Our Health Anywhere, Anytime Biosensors are rapidly becoming part of our everyday life. As technology advances, we may soon be able to monitor many aspects of our health at home, in real time, and without needles. Traditionally used in medical practice to monitor patient status, biosensors have recently started to be broadly marketed for wellness and fitness applications. These […] July 27, 2020 - 6 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
In Depth 1 Jun 2020 How Personal Genomics Companies Are Changing Drug Development In recent years, companies offering direct-to-consumer genomics tests have started switching the business model and venturing into drug development. Amidst criticism on data protection and lack of transparency, personal genomics companies are leveraging their unique position to generate genomics data to strike lucrative deals with pharma companies. Thanks to cheaper data acquisition and convenient analysis, […] June 1, 2020 - 6 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
In Depth 11 Feb 2019 CRISPR: One Patent to Rule Them All The gene editing tool CRISPR-Cas9 has revolutionized research in biology. With several parties fighting for the rights to the technology’s intellectual property, how difficult is it for third parties to access this coveted technology? The CRISPR patent dispute is quite unique. While universities usually work together to disseminate innovation and knowledge, in the CRISPR case […] February 11, 2019 - 5 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
In Depth 14 May 2018 Could Stem Cells Replace Animal Testing in Drug Development? Animal testing is a crucial part of developing new medicines, but it comes with ethical concerns. Stem cells could eventually make it unnecessary. Nowadays you can order a rat with Parkinson’s disease or a dog with diabetes as you would any product on the internet. But the ethical issues surrounding animal testing beg the question: […] May 14, 2018 - 6 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
News and Trends 20 Dec 2017 How to Deal with Regulations to Get Approval for CAR-T Cells The biotech industry is diving into the field of highly individualized gene and cell therapy products. The first CAR-T therapy has just been approved in the US and other breakthrough technologies like mRNA and CRISPR have a foot in the door. But getting to the market is not straightforward, not only for developers but also for […] December 20, 2017 - 8 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
In Depth 20 Jul 2017 SHIVA Trial: France’s Big Shot at Precision Medicine for Cancer SHIVA01 and SHIVA02 are large-scale trials run in France to evaluate the efficacy of precision medicine that have created ripples in the oncology field. Although molecular alterations are shared among different types of cancer, drug development today is still mainly based on tumor localization. The only recent exception is MSD’s Keytruda (pembrolizumab) an antibody approved by […] July 20, 2017 - 5 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
In Depth 12 Jul 2017 Genomic Testing in Oncology: From Single Genes to Whole Genomes Personalized medicine would be nothing without genomic testing tools. Here’s an overview of how the field has rapidly evolved in the past years. BRCA (BReast CAncer) is one of the most famous gene variants for breast cancer testing. But aside from being a game-changer from a scientific perspective, it also changed the laws of genomic testing. […] July 12, 2017 - 5 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
News and Trends 14 Jun 2017 Results are in for Europe’s First Biobanking Study on HPV Cervical Cancer The RAIDs consortium made its closing event last week. After 4.5 years of studies, it has managed to change our appreciation of HPV cervical cancer towards building intelligent targeted therapy designs. Every year in Europe, 16,000 women die from cervical cancer and another 34,000 are newly diagnosed, which makes it the second most frequent form […] June 14, 2017 - 5 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email
News and Trends 18 Jan 2017 It’s Not Just Regulations: 9 Other Reasons Advanced Therapies Fail For advanced therapy medicinal products (ATMPs), the regulatory process is a major challenge to reach the market; but it’s only part of the picture. Here are the top 9 other pre-approval reasons these cell and gene therapies fail. Sound Scientific Rationale + Good Product = Successful Outcome.” Paula Salmikangas, Committee for Advanced Therapies (CAT) Chairman […] January 18, 2017 - 7 minutesmins - By Timothé Cynober Share WhatsApp Twitter Linkedin Email