Sponsored Archives

Impacting vaccine development: COVID-19 and its implications for the future of vaccines

The development of COVID-19 vaccines was an unprecedented achievement at a time of urgent medical need. We explore the novel technology platforms that went into their development and consider their long-term impact on vaccine research. Ever since the first vaccine against smallpox in the late 1700s, vaccines have gained a reputation as a critical tool […]

November 3, 2022 - 8 minutesmins - By Sudha Sundaram

Using the power of proteomics to predict immunotherapy responses in melanoma and beyond

Next-generation proteomics has a vital role to play in the search for new biomarkers of immunotherapy response. Recent studies in melanoma presented at the European Society for Medical Oncology (ESMO) Congress highlight how these insights have the potential to transform cancer care. The recent success of immunotherapies that manipulate the patient’s immune system to recognize […]

September 27, 2022 - 6 minutesmins - By External Contributor

Metagenomics: unlocking the secrets of microbial communities

The combination of advanced sequencing technologies and user-friendly data analysis solutions is bringing metagenomics into the reach of more scientists, creating new opportunities to ask and answer exciting research questions. New ways to look at microbes Metagenomics is a relatively new field that is radically changing how microbial analyses are performed and making it possible […]

August 30, 2022 - 6 minutesmins - By Julia Kaiser

organoids in a dish, drug development, patient relevant model

The organoid era: bringing patient-relevant preclinical models to the lab

Drug development is a lengthy and costly process that takes at least 10 years on average from drug discovery to commercialization, requiring billions of dollars in investment. However, over 90% of new drugs that are tested in clinical trials fail. Organoids — three-dimensional, patient-derived mini-organs in a dish — offer a solution to this challenge. […]

July 12, 2022 - 7 minutesmins - By Sudha Sundaram

decentralized trial virtual clinical trial

The trial of the future: using digital technologies to enable decentralized trials

Conducting a successful clinical trial is by no means an easy endeavor; it requires extensive planning to ensure that multiple resource- and time-intensive activities are completed seamlessly. In a post-Covid-19 world that is heavily reliant on virtual tools, the healthcare industry is leveraging digital health technologies to optimize clinical trials. Clinical trial planning starts off […]

July 1, 2022 - 7 minutesmins - By Sudha Sundaram

covid-19 vaccine bottles, manufacture supply line, vaccine development

How a global network accelerated the development of a virus-like particle vaccine against Covid-19

Vaccines are among the most effective ways to improve and protect human health. Whereas vaccines in Europe and North America are regarded as part of the general medical plan, vaccine supply has always been a pressing issue in African countries. In the current Covid-19 pandemic, the ability to develop and manufacture vaccines in Africa instead […]

June 23, 2022 - 5 minutesmins - By Ute Boronowsky

Gene therapy: can CDMOs solve the manufacturing bottleneck?

The gene therapy market is booming. Viral vectors, the key delivery systems for gene therapies, are playing an increasing role in the development of biologics. But the growing need for viral vectors and their plasmid building blocks have resulted in a manufacturing bottleneck. Can contract manufacturing organizations cope with the rising demand? In 2019, Zolgensma, a […]

June 7, 2022 - 7 minutesmins - By Ute Boronowsky

CAR-T cell therapy, cancer therapy, cell therapy

Combination Therapies: Opportunities for Improved CAR-T Cell Therapy?

Chimeric antigen receptor (CAR) cell therapy offers hope where other cancer therapies have failed. However, CAR-T therapy still faces limitations. How can combination therapy enhance its success in treating cancer? Combination therapy involves pairing two cancer treatments with each other to enhance the benefits of both. CAR-T cell therapy, which uses white blood cells called […]

March 10, 2022 - 6 minutesmins - By Alexander Burik

Merck, drug development, lab work, lab worker, scientist

Top Reasons to Outsource Your Early Clinical Pipeline to a CDMO

Biotech firms partner with contract development and manufacturing organizations (CDMOs) to leverage their expertise in process development, optimization, and scale-up. In this article, we share an exclusive sneak-peek into a recent survey, which explores the main reasons why biotech companies collaborate with CDMOs at different stages of drug development. To make a new drug candidate […]

January 26, 2022 - 8 minutesmins - By Sudha Sundaram

bioreactor, cell culture expansion, perfusion, biomanufacturing

How to Make Cell Culture Expansion Easy

Cell culture expansion for biotherapeutic development has traditionally involved a series of time-consuming, labor-intensive batch cultures that are susceptible to contamination. Cell culture expansion using a perfusion process promises easy scalability, ensures high productivity gains, and saves time and costs during large-scale biomanufacturing. Cell culture is a crucial tool in the biotech sector. Applications range […]

January 18, 2022 - 7 minutesmins - By Sudha Sundaram

biostatistics, biostatistician, clinical trial management

Why Biostatisticians are Essential for Successful Clinical Trial Management

The role of biostatisticians goes far beyond analyzing data at the end of a clinical study. Instead, they should be involved in clinical trial management right from the start to maximize the chances for a new drug’s market approval. Biostatisticians in clinical trial management have a long to-do list. They advise on study design, calculate […]

January 4, 2022 - 5 minutesmins - By Ute Boronowsky

clinical trial, robotic automation, robot hand, lab automation

Streamlining Clinical Trial Execution with Robotic Process Automation

Conducting clinical trials on time ensures that innovative treatments can reach patients in need. In the face of logistical challenges caused by the Covid-19 pandemic, the clinical trial sector has faced major pressure to come up with innovative solutions to streamline processes and continue running trials. One such solution is robotic process automation (RPA), which […]

December 15, 2021 - 6 minutesmins - By Sudha Sundaram

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