Startup Scout 22 Sep 2022 Cartography Biosciences unearths cancer immunotherapy targets Despite its meteoric growth in the last twenty years, cancer immunotherapy research is hamstrung by a lack of viable drug targets. Cartography Biosciences is using a single-cell sequencing approach to meet this demand. Immuno-oncology as a field barely existed 20 years ago, but has rapidly grown into a thriving field of biotechnology research. This has […] September 22, 2022 - 5 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 15 Sep 2022 Adva Biotechnology is using artificial intelligence to manufacture cell therapies The manufacturing of cell therapies is highly complex, often depending on skilled manual labor. The Israeli startup Adva Biotechnology aims to use automation, optical sensing and artificial intelligence to remove the manual component from the process. Cancer cell therapies such as CAR-T immunotherapies have demonstrated enormous potential for treating forms of blood cancer. Currently available […] September 15, 2022 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 8 Sep 2022 Stratosvir is overcoming the viral immunotherapy delivery bottleneck The U.K. startup Stratosvir is working to tackle the barriers to developing viral immunotherapies for cancer, including allowing intravenous delivery and making it possible to dose multiple times. Cancer immunotherapies have made great strides in the last decade, with some of the most important advances including CAR-T cell therapy and checkpoint inhibitors. One oncology field […] September 8, 2022 - 6 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 26 Aug 2022 Epic Bio makes gene therapies by editing the epigenome CRISPR-Cas9 genome editing has changed the game for gene therapy, but carries safety risks when cutting DNA. The new U.S. firm Epic Bio aims to reduce these risks by targeting epigenetic controls on gene expression. The development of the genome-editing tool CRISPR-Cas9 caused a paradigm shift in the biotech industry because it made it easier […] August 26, 2022 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 1 May 2020 Belgian Company Harnesses Lab-on-a-Chip Technology to Diagnose Disease The Belgian startup miDiagnostics is developing technology to diagnose diseases quickly, accurately, and at the point-of-care using a silicon lab-on-a-chip and nanoscale-precision microfluidics. Having good diagnostics in place can save lives. This principle is especially true in times of crisis, such as the current coronavirus pandemic. However, producing good diagnostics isn’t a simple task. In […] May 1, 2020 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 17 Apr 2020 Amphista Therapeutics Is Silencing Disease Proteins to Treat Cancer Amphista Therapeutics, based in Glasgow, Scotland, is the latest company to develop drugs called PROTACs, which are designed to make the cell degrade harmful proteins to treat cancer. Small molecule drugs have shown incredible potential for the treatment of cancer by blocking harmful proteins in the cell. However, many promising protein targets for cancer treatments […] April 17, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 27 Mar 2020 This Startup is Making a Cancer Vaccine out of Viruses Valo Therapeutics is operating both in the UK and Finland to develop a cancer vaccine based on a virus designed to kill tumors. Mission: To combine two different immunotherapy techniques — oncolytic viruses and cancer vaccines — into one treatment for solid tumors. Immunotherapy has transformed the cancer treatment landscape, offering therapies such as checkpoint […] March 27, 2020 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 13 Mar 2020 This Startup Hits Hidden Proteins to Make Cancer Immunotherapies With one foot in Belgium and another in the US, Orionis Biosciences combines US and European talent to develop cancer immunotherapies targeting difficult protein targets. Mission: To fight cancer with two technologies. The first is modifying immune proteins called cytokines to trigger the body to produce specific immune cells against a tumor. The second is […] March 13, 2020 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 6 Mar 2020 This Startup Is Developing a DIY Biomarker Diagnostics Kit The Swedish medical device startup Qlife is developing a diagnostic kit that patients can use at home to better control chronic diseases. Mission: To make convenient diagnostics for patients with a home-use kit that they can use to monitor blood biomarkers in chronic conditions such as arthritis. Chronic disorders such as cardiovascular disease and diabetes […] March 6, 2020 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 28 Feb 2020 This Startup Is Automating the Manufacture of Gene and Cell Therapies In London, the firm Ori Biotech is developing an automated way to manufacture gene and cell therapies, a bottleneck for many biotech companies. Mission: To develop a robotic system to automate the labor-intensive tasks involved in manufacturing cell and gene therapies, such as gene transduction and cell expansion. Gene and cell therapies are maturing as […] February 28, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 21 Feb 2020 This Startup is Developing Anti-Aging Antibodies The Heidelberg-based startup Velabs Therapeutics aims to make anti-aging drugs that selectively destroy ‘aged’ cells in the body. Mission: To develop antibody drugs using microfluidics technology that can kill old or ‘senescent’ cells, which have been linked to the development of age-related conditions such as cardiovascular disease, dementia, and macular degeneration. While there are various […] February 21, 2020 - 4 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email
Startup Scout 14 Feb 2020 Novadiscovery Carries out Clinical Trials using AI and Simulations Novadiscovery, based in Lyon, France, is developing AI-based simulation technology to predict clinical trial outcomes and cut their running costs. Mission: To predict the outcomes of clinical trials in silico using a combination of artificial intelligence (AI) and computational models of the biology underlying the disease. Clinical trials cost the healthcare industry billions of euros […] February 14, 2020 - 3 minutesmins - By Jonathan Smith Share WhatsApp Twitter Linkedin Email