You searched for Humanized antibody

News and Trends 12 Oct 2015

Roche dishes out €509M for a Humanized antibody against Rheumatoid Arthritis

Adheron Therapeutics is a small California (US) biotech which has developed a phase I monoclonal antibody (mAb) therapy for inflammatory diseases such as Rheumatoid Arthritis. Using the mAb humanisation platform licensed from Abzena (a life Sciences group from Cambridge, UK), Adheron Therapeutics will now be acquired by Swiss giant Roche for €509M. Abzena, based in […]

October 12, 2015 - 2 minutesmins - By Dani Bancroft

Best in Biotech 8 Feb 2024

Fourteen biotech companies spearheading the antibody drug conjugate industry

The antibody-drug conjugate market has gained significant traction recently. Discover some of the top ADC companies in the industry.

February 8, 2024 - 18 minutesmins - By Jules Adam

In Depth 26 Jul 2023

Antibody drug conjugates: BiVictriX drives a new era in cancer medicine

The first-ever antibody-drug conjugate (ADC) to be approved, gemtuzumab ozogamicin, raised hope for a new class of drugs to treat cancer. But the drug was then withdrawn following a black box warning after patients experienced adverse side effects, and there had been fatalities. But this didn’t discourage biopharmas looking to create safer alternatives from expediting […]

July 26, 2023 - 7 minutesmins - By Roohi Mariam Peter

News and Trends 20 Jul 2023

Mage Biologics created to develop oral antibody therapy for ulcerative colitis

TVM Capital Life Science and specialty pharma company Tillotts Pharma are to jointly invest up to $28 million in a newly formed U.S.-based biotechnology company, Mage Biologics Inc. TVM will invest with its TVM Life Science Innovation II SCSp (TVM LSI II) fund and will provide strategic advice to Mage Bio. Mage Bio is the […]

July 20, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 5 Oct 2022

Transcenta monoclonal antibody gets FDA clearance

Transcenta Holding Limited says its TST004 humanized monoclonal antibody targeting MASP2, has received IND clearance from the U.S. Food and Drug Administration (FDA). MASP2, mannose-binding protein-associated serine protease 2, is a key enzyme in the lectin pathway initiation of complement activation. Studies have shown that lectin pathway activation contributes to multiple human diseases such as […]

October 5, 2022 - 2 minutesmins - By Jim Cornall

News and Trends 11 Dec 2017

New Antibody-Drug Conjugate Offers Hope to Hard-to-Treat Cancer Patients

ADC Therapeutics has tested its antibody-drug conjugate technology in drug-resistant cancers, yielding encouraging results. Swiss biotech ADC Therapeutics is one of our top biotechs of the year after it brought in a massive $200M (€170M) fundraising round. The company develops antibody-drug conjugates (ADCs) for the treatment of hematological cancers and solid tumors. Results from two Phase I studies […]

December 11, 2017 - 3 minutesmins - By Alex Dale

More News! 5 Dec 2017

PayPal Co-Founder Backs Israeli Biotech Attacking NASH with an Antibody

ChemomAb kicked off its antibody efforts as a company in 2011, and its $10M Series B has attracted none other than Peter Thiel. Israeli biotech has been attracting quite sizeable funds recently, largely those of UK investment outfit Arix Bioscience. Yesterday it was announced that Peter Theil, co-founder of PayPal and assassin of Gawker, led […]

December 5, 2017 - 2 minutesmins - By Evelyn Warner

News and Trends 6 Sep 2017

Tiziana‘s Antibody Formulation Enters Phase IIa Trial for Liver Disease Treatment

Tiziana makes moves towards a €37B market with an oral monoclonal antibody (mAb) formulation to treat non-alcoholic steatohepatitis (NASH) . Tiziana, which has previously developed compounds targeting the second most deadly form of cancer, has produced a novel formulation of the anti-CD3 mAb, Foralumab. The biologic will be tested in patients with NASH and other […]

September 6, 2017 - 3 minutesmins - By Alex Dale

Interview 8 Jun 2017

Cambridge Antibody Technology: The History of the UK’s Best Biotech

CAT was the first of Greg Winter’s three antibody-related companies and one of the UK’s biggest success stories in biotech. How did he pull it off? Sir Greg Winter is one of the biggest names in European biotech. As a Professor of Biochemistry at Cambridge University, he developed phage display technology that became the foundation […]

June 8, 2017 - 7 minutesmins - By Evelyn Warner

Interview 15 May 2017

Meet the CEO developing the Next Generation of Antibody Therapeutics

Crescendo Biologics has positioned itself as the successor of Cambridge Antibody Technology and a new rival to Morphosys. We interviewed CEO Peter Pack. Peter Pack started working in life science 25 years ago — “quite a long time ago,” he laughs. “I’m an old guy now.” Now the CEO of Crescendo Biologics, whose Humabody platform […]

May 15, 2017 - 8 minutesmins - By Evelyn Warner

News and Trends 28 Nov 2014

One Billion Strategic Oncology Alliance for the Second Largest Antibody Technology Platform

Oxford BioTherapeutics and Menarini Group have initiated the first-in-human clinical study of OBT357, a novel enhanced antibody for the treatment of acute myeloid leukemia (AML). This is the first of five development programs between the two companies to enter the clinic in a $1 billion strategic oncology alliance. Oxford BioTherapeutics and the Menarini Group established their […]

November 28, 2014 - 2 minutesmins - By Julie Lellouche

Best in Biotech 29 Feb 2024

6 biotech companies making a difference in pediatric care

Take a closer look at six pediatric companies taking innovative approaches to tackle illnesses affecting children.

February 29, 2024 - 8 minutesmins - By Willow Shah-Neville

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