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gene therapy osteoarthritis genequine2 1

News and Trends 14 Dec 2017

German Biotech’s Gene Therapy for Osteoarthritis Plucked by US Pharma

GeneQuine’s gene therapy for osteoarthritis in the knee has been acquired by US pharma company Flexion Therapeutics for up to $64M. GeneQuine is developing a gene therapy for the treatment of osteoarthritis. It uses helper-dependent adenoviruses, which provide long-term expression, a higher packaging capacity, reduced immunogenicity and they do not integrate into the host genome. It seems like yesterday […]

December 14, 2017 - 3 minutesmins - By Alex Dale

lung cancer triple therapy 1

News and Trends 7 Dec 2017

Taking Aim at Lung Cancer: New Triple Combination Therapy Boosts Survival

A new first-line combination therapy for advanced non-squamous non-small-cell lung cancer improved progression-free survival during a Phase III trial. Scientists based at the Lung Clinic Grosshansdorf, Hamburg, and Centre Hospitalier Universitaire Vaudois, Lausanne, have presented the results of a Phase III study at the ESMO Immuno Oncology Congress 2017. The study was the first to investigate a combination […]

December 7, 2017 - 3 minutesmins - By Alex Dale

psoriasis treatment approval morphosys 1

News and Trends 23 Nov 2017

Janssen’s Psoriasis Drug is Given a Thumbs Up for Use in Europe

Following its FDA approval in July, MorphoSys’ anti-IL23 antibody has been approved to treat moderate-to-severe psoriasis by the European Commission. German biotech, MorphoSys, is a leader in the field of therapeutic antibodies for series diseases including cancer, arthritis and Alzheimer’s. Today, the company has announced that the licensee, Janssen, has received approval from the European Commission […]

November 23, 2017 - 3 minutesmins - By Alex Dale

Heidelberg Pharma ADCs Amanitin 1

News and Trends 21 Nov 2017

German Biotech Reels in €34M for its Cancer-Killing Technology

Heidelberg Pharma is developing Antibody Targeted Amanitin Conjugates (ATACs), which combine antibody-drug conjugate technology with the toxin, Amanitin. Heidelberg Pharma has attracted over €34M of investment to support the development of its Antibody Targeted Amanitin Conjugates (ATACs) technology. The biotech, formerly Wilex, is developing drugs for cancer and autoimmune diseases, with the hope that the addition of Amanitin to antibody-drug conjugate (ADC) technology could produce […]

November 21, 2017 - 1 minutemin - By Alex Dale

Trim Away protein function2 1

News and Trends 20 Nov 2017

British and German Scientists Chuck Proteins in the Trash to Uncover their Function

Trim-Away removes a protein to uncover its true function, which will support disease research and potentially the development of new therapies. Scientists at the Medical Research Council in the UK and the Max Planck Institute in Germany have discovered Trim-Away, a new technique that can remove a protein from a cell so that its true function can […]

November 20, 2017 - 3 minutesmins - By Alex Dale

anne portwich 1

Interview 20 Nov 2017

Thinking of Leaving Academia? Read this VC Partner’s Story

Anne Portwich, Partner at venture capital firm LSP, told me about her career path and how to succeed in the life science industry. Anne Portwich became the first woman partner at LSP in 2011. The fund has raised more than $1B since it was founded more than 25 years ago, and the cash goes mainly to […]

November 20, 2017 - 9 minutesmins - By Evelyn Warner

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cancer sensor tp53 germany 1

News and Trends 16 Nov 2017

German Cancer Sensor Raises the Alarm and Puts the Fire Out

No need to call the fire brigade! The University of Dresden’s cancer sensor spots a mutation to p53, the most important cancer gene, and kills the cell. Researchers at the University of Dresden, Germany, have developed a molecular sensor that detects a mutation in tumor protein p53 – implicated in 50% of cancers – and kills […]

November 16, 2017 - 3 minutesmins - By Alex Dale

hummingbird diagnostics cancer alzheimer parkinson

News and Trends 16 Nov 2017

German Diagnostics Firm Tackles Early Detection of Cancer, Alzheimer’s and Parkinson’s

Hummingbird Diagnostics has teamed up with Saarland University to develop molecular diagnostics that can detect serious diseases early using blood samples. Based in Heidelberg, Germany, Hummingbird Diagnostics develops early diagnostics in multiple disease areas, ranging from cancer to cardiovascular and neurodegenerative disease. Its technology is based in the detection of miRNA, molecules that are involved […]

November 16, 2017 - 2 minutesmins - By Clara Rodríguez Fernández

HIV vaccination primates Germany 1

News and Trends 16 Nov 2017

German Scientists Test Out New HIV Vaccine Combinations in Animals

Scientists from the German Primate Center have investigated the impact of the delivery route and order of components on the success of an HIV vaccine. With more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million infected each year, something needs to be done. Researchers from the German […]

November 16, 2017 - 3 minutesmins - By Alex Dale

moderna biontech personalized cancer vaccine

News and Trends 15 Nov 2017

US Biotech Unicorn Steps up Competition for BioNTech’s mRNA Personalized Cancer Vaccine

Moderna Therapeutics has started dosing patients with an mRNA-based personalized cancer vaccine that resembles another one being developed by BioNTech. Moderna Therapeutics has announced the start of a Phase 1 study with mRNA-4157, a therapy consisting of a cancer vaccine that is tailored to each patient’s individual tumor. In order to make this personalized treatment, […]

November 15, 2017 - 2 minutesmins - By Clara Rodríguez Fernández

topas therapeutics timm jessen interview

Interview 15 Nov 2017

Therapeutic Nanoparticle Companies Are Rare: Meet the CEO of One of Them

In our last BIO Europe interview, I caught up with CEO Timm Jessen of Topas Therapeutics to hear about the company’s nanoparticles. Founded in 2013 as a spinout from Evotec, Topas Therapeutics is developing nanoparticles for a whole range of diseases and with CEO Timm Jessen at the helm. He told me the story of […]

November 15, 2017 - 4 minutesmins - By Evelyn Warner

Evotec CEO Werner Lanthaler Biotech Innovation Partnerships

Interview 9 Nov 2017

Interview with Europe’s Leader in Biotech Partnerships

I talked with Werner Lanthaler, CEO of Evotec, during Bio Europe 2017 to ask him what the key is to his company’s great success in supporting biotech innovation and establishing strategic partnerships. Evotec started off as a contract research organization in Hamburg back in 1993. Today it has over 2,000 employees worldwide, its own pipeline […]

November 9, 2017 - 2 minutesmins - By Clara Rodríguez Fernández

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