Cell therapy Archives

bone marrow transplant blood cancer kiadis pharma cell therapy

News and Trends 13 Nov 2019

Mass Layoffs as Dutch Biotech Cancels Phase III Cell Therapy Trial

The Dutch company Kiadis Pharma has discontinued the development of a cell therapy in blood cancer, laid off half of its workforce, and switched focus to other, less advanced cell therapy programs. The abandoned phase III trial was testing Kiadis Pharma’s lead cell therapy for the treatment of graft-versus-host disease, a complication of stem cell […]

November 13, 2019 - 2 minutesmins - By Jonathan Smith

cancer vaccine virus ervaxx cell therapy

News and Trends 6 Nov 2019

UK Biotech Launched to Target ‘Dark Antigens’ with Cancer Vaccines

The London-based startup Ervaxx has launched with a €15.8M Series A round to develop cancer vaccines and cell therapies that target ‘dark antigens’ — normally silent genes in the genome that are expressed in cancer cells. Ervaxx’s Series A round was funded by the transatlantic venture capital firm SV Health Investors, as well as an […]

November 6, 2019 - 2 minutesmins - By Jonathan Smith

EU regulations cell gene therapy clinical trials

News and Trends 5 Nov 2019

EU Regulations Are Holding Back Gene and Cell Therapy Clinical Trials

European regulations might be responsible for lower numbers of advanced therapy clinical trials running in the region when compared to the US and Asia. Europe has historically been a pioneer in advanced therapies, such as cell and gene therapy. Europe was the first region to approve a gene therapy, and it boasts the highest number […]

November 5, 2019 - 4 minutesmins - By Clara Rodríguez Fernández

News and Trends 14 Oct 2019

Mogrify Raises €15M Series A to Chase the ‘Holy Grail’ of Cell Therapy

Cambridge-based Mogrify has raised €14.5M to develop a technology that could allow scientists to transform any human cell into another cell type without the arduous process of turning them into a stem cell first. The Series A round was led by Ahren Innovation Capital, an investment firm founded by science entrepreneurs from the UK […]

October 14, 2019 - 2 minutesmins - By Clara Rodríguez Fernández

stem cell therapy deafness rinri therapeutics

Startup Scout 11 Oct 2019

This Biotech Is Developing a Stem Cell Therapy for Deafness

Sheffield is one of the UK’s historic industrial bases. It also hosts the biotech Rinri Therapeutics, which is developing a stem cell therapy to treat deaf patients who are not eligible for cochlear implants. Mission: To develop a stem cell therapy for a rare form of deafness where the neuronal wiring underlying the auditory system […]

October 11, 2019 - 3 minutesmins - By Jonathan Smith

lightcast discovery cell therapy cambridge uk

Startup Scout 27 Sep 2019

This Biotech Can Screen CAR T-Cells Using Only Light and Microfluidics

Based in Cambridge, UK, Lightcast Discovery is developing microfluidics technology that automates cell screening experiments by using lasers. Mission: To automate cell screening experiments, such as those used when screening CAR T-cell immunotherapies. This would let companies test therapies in complex cell experiments, such as cell-to-cell interactions, which are difficult with traditional drug-screening tools. Cell […]

September 27, 2019 - 3 minutesmins - By Jonathan Smith

grunenthal mesoblast chronic low back pain

News and Trends 11 Sep 2019

Grünenthal to Pay up to €900M for Chronic Low Back Pain Cell Therapy

The German pharmaceutical company Grünenthal has licensed a donor cell therapy for chronic low back pain from the Australian biotech Mesoblast in a deal that could be worth over €900M. Under the terms of the deal, Grünenthal will gain exclusive rights to commercialize Mesoblast’s cell therapy for chronic low back pain in Europe and Latin […]

September 11, 2019 - 2 minutesmins - By Jonathan Smith

blood cancer stem cell therapy brain cancer

News and Trends 11 Sep 2019

Italian Biotech Raises €13M to Test Stem Cell Therapy for Cancer

The Italian biotech Genenta Science has raised €13.2M in a private round to fund two ongoing phase I/II trials of its stem cell therapy Temferon for blood and brain cancer. Genenta Science will use the money to fund two European phase I/II trials, which the company launched in March. One trial is testing the stem […]

September 11, 2019 - 3 minutesmins - By Jonathan Smith

gene therapy cell therapy advanced therapy 4BIO

News and Trends 9 Sep 2019

4BIO Capital Raises €45M Fund to Invest in Advanced Therapies

The London-based life sciences investor 4BIO Capital has raised €45M in the first close of a fund to nurture companies developing advanced therapies such as gene and cell therapies. This is the first closing of 4BIO’s second fund, called 4BIO Ventures II, which is expected to total €136M ($150M) by late 2020. The fund will […]

September 9, 2019 - 3 minutesmins - By Jonathan Smith

cancer cell therapy immunotherapy achilles therapeutics

News and Trends 3 Sep 2019

UK Biotech’s Personalized Immunotherapy gets €110M Series B Boost

The UK company Achilles Therapeutics has raised €110M (£100M) to test its personalized cancer cell immunotherapies in humans for the first time. The large Series B round will fund two phase I/IIa clinical trials of Achilles’ preclinical immunotherapy which are expected to start this year: one in non-small cell lung cancer and the other in […]

September 3, 2019 - 2 minutesmins - By Jonathan Smith

dendritic cell immunicum cancer immunotherapy cell therapy

News and Trends 29 Aug 2019

Off-the-Shelf Kidney Cancer Immunotherapy More Than Doubles Recovery in Phase II

An off-the-shelf cancer immunotherapy developed by the Swedish biotech Immunicum has eradicated kidney tumors in 11% of treated patients compared with just 4% of patients given standard treatments in a phase II trial. Immunicum is developing a cell immunotherapy to treat metastatic renal cell carcinoma. This advanced form of kidney cancer is particularly hard to […]

August 29, 2019 - 3 minutesmins - By Jonathan Smith

celgene immatics cancer cell immunotherapy

News and Trends 28 Aug 2019

Celgene and Immatics Sign Deal Worth Over €1.35B to Develop Cancer Immunotherapies

The US company Celgene has obtained options to three cancer immunotherapy programs from the German biotech Immatics in a deal worth more than €1.35B ($1.5B). Immatics is to receive an upfront payment of €67.5M ($75M), along with up to €455M ($505M) in developmental milestones and royalties for each immunotherapy program. In each program, Immatics will […]

August 28, 2019 - 3 minutesmins - By Jonathan Smith

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